Evidence map›Paper›PMID 29237753›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney.

Frans Schutgens, Maarten B Rookmaaker, Francis Blokzijl, Ruben van Boxtel, Robert Vries, Edwin Cuppen, Marianne C Verhaar, Hans Clevers

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Regenerative Role of Lrig1+ Cells in Kidney Repair.Journal of the American Society of Nephrology : JASN · 2024
    Article
  5. Tubuloid culture enables long-term expansion of functional human kidney tubule epithelium from iPSC-derived organoids.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Frans SchutgensHubrecht Institute-Royal Netherlands Academy of Arts and Sciences, 3584 CT Utrecht, The Netherlands.
Maarten B RookmaakerDepartment of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Francis BlokzijlCenter for Molecular Medicine, Department of Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Ruben van BoxtelCenter for Molecular Medicine, Department of Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Robert VriesHubrecht Organoid Technology, 3584 CM Utrecht, The Netherlands.
Edwin CuppenCenter for Molecular Medicine, Department of Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.ORCID 0000-0002-0400-9542
Marianne C VerhaarDepartment of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Hans CleversHubrecht Institute-Royal Netherlands Academy of Arts and Sciences, 3584 CT Utrecht, The Netherlands; h.clevers@hubrecht.eu.
University Medical Center Utrecht · NLRoyal Netherlands Academy of Arts and Sciences · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During kidney development, progressively committed progenitor cells give rise to the distinct segments of the nephron, the functional unit of the kidney. Similar segment-committed progenitor cells are thought to be involved in the homeostasis of adult kidney. However, markers for most segment-committed progenitor cells remain to be identified. Here, we evaluate

Indexed as

AnimalsEpithelial CellsMiceMice, TransgenicNephronsOrganogenesisReceptors, Tumor Necrosis FactorStem CellsReceptors, Tumor Necrosis FactorTnfrsf19 protein, mousedevelopmentkidneylineage tracingorganoidsstem cell

Identifiers

PMID29237753
PMCPMC5748200
OpenAlexW2773168637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.