Evidence map›Paper›PMID 29237741›Full record

ArticleGenes & development2017

Liberating cohesin from cohesion.

Kerry Bloom

Open access · diamondAbstract readComment
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kerry BloomDepartment of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
University of North Carolina at Chapel Hill · US

Funding

Structure and Function of a Eukaryotic CentromereR37GM032238 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BLOOM, KERRY S, YEH, ELAINE YING · 2011 to 2020
$5.2M
NIGMS NIH HHS R37 GM032238
6 · The paper itself

Abstract

Cohesin was identified through its major role in holding sister chromatids together. We are learning through analysis of cohesin and other members of the protein family (SMC [structural maintenance of chromosomes]) and their regulators that these ring complexes contribute to chromosome organization and dynamics throughout the cell cycle. We need to consider not only how ring complexes are regulated but how they interact with their fluctuating chromatin substrate.

Indexed as

AcetyltransferasesCell Cycle ProteinsChromatidsChromatinChromosomal Proteins, Non-HistoneCohesinsInterphaseAcetyltransferasesCell Cycle ProteinsChromatinChromosomal Proteins, Non-HistoneCohesinscentromerechromatin territorieschromosome segregationcohesin acetyltransferasesESCO1/2sister chromatid cohesion

Identifiers

PMID29237741
PMCPMC5749159
OpenAlexW2773822729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.