ReviewCanadian family physician Medecin de famille canadien2017
Diagnosis and treatment of pruritus.
Review in Canadian family physician Medecin de famille canadien, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Electrical neurostimulation for the treatment of chronic pruritus: A systematic review.Experimental dermatology · 2022Pooled it
- The association between water hardness and xerosis-Results from the Danish Blood Donor Study.PloS one · 2021Pooled it
- Evaluation of the efficacy and safety of artemether emulsion on localized senile pruritus: A randomized pilot study.Medicine · 2022Trial
- Pruritus in Europe's Aging Populations: Regional and National Patterns, 1990-2023, and Forecasts to 2050: A Systematic Analysis for the Global Burden of Disease Study 2023.Clinical, cosmetic and investigational dermatology · 2026Article
- Pruritus in Palliative Care: A Narrative Review of Essential Oil-Based Strategies to Alleviate Cutaneous Discomfort.Diseases (Basel, Switzerland) · 2025Review
- Soothing the Itch: The Role of Medicinal Plants in Alleviating Pruritus in Palliative Care.Plants (Basel, Switzerland) · 2024Review
- Article
- Treating Chronic Pruritus: Are We at the Threshold of a Breakthrough?Skin (Milwood, N.Y.) · 2024Article
- Review
- Chronic kidney disease-associated pruritus: what is known and its application in children.Pediatric nephrology (Berlin, Germany) · 2024Review
- Article
- Chronic Kidney Disease-Associated Pruritus and Quality of Life: Learning from Our Patients.Journal of clinical medicine · 2023Review
- Alleviating symptoms in patients undergoing long-term hemodialysis: a focus on chronic kidney disease-associated pruritus.Clinical kidney journal · 2023Review
- Knowledge, Attitude and Practice for Pruritus Management in Physicians and Patients with Diabetes.Clinics and practice · 2022Article
- Clinical Manifestations and Genetic Influences in Sulfonamide-Induced Hypersensitivity.Drug, healthcare and patient safety · 2022Review
- Article
- An itchy erythematous papular skin rash as a possible early sign of COVID-19: a case report.Journal of medical case reports · 2020Article
- Article
Corrections and comments
- Erratum issuedCorrection.2018
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe an approach that allows for a streamlined assessment and accurate differentiation of most patients with itch in primary care and to provide an update on the available nonpharmacologic, topical, and systemic therapies. SOURCES OF INFORMATION: MEDLINE (Ovid) and PubMed were searched for the key words MAIN MESSAGE: A good body of evidence from high-quality trials does not exist for treatment of pruritus, and the treatments that do exist are inconsistent in their success. The dominant causes of generalized itch are xerosis and eczema. Most patients will improve with nonpharmacologic therapy including frequent moisturization. If this avenue fails, further investigations are warranted to help guide subsequent treatment with any of the many cause-specific topical and systemic approaches available.
conclusionChronic itch can be debilitating for patients. The approach described allows for a streamlined assessment and accurate differentiation of most patients with itch in primary care.
Indexed as
Identifiers
29237630PMC5729138What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.