ArticleEuropean journal of pharmacology2018
Prokinetic effects of neurokinin-2 receptor agonists on the bladder and rectum of rats with acute spinal cord transection.
Article in European journal of pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Recent Developments in On-Demand Voiding Therapies.The Journal of pharmacology and experimental therapeutics · 2024Review
- Rapid-Onset, Short-Duration Induction of Colorectal Contractions in Anesthetized, Adult, Male Rats.The Journal of pharmacology and experimental therapeutics · 2024Article
- Molecular Mechanisms of Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury.International journal of molecular sciences · 2023Review
- [LysJournal of basic and clinical physiology and pharmacology · 2023Article
- Neurokinin 2 receptor-mediated bladder and colorectal responses in aged spinal cord injured rats.Spinal cord · 2021Article
- Congenital ablation ofAmerican journal of physiology. Endocrinology and metabolism · 2021Article
- Diminished enteric neuromuscular transmission in the distal colon following experimental spinal cord injury.Experimental neurology · 2020Article
- Chronic, Twice-Daily Dosing of an NK2 Receptor Agonist [LysJournal of neurotrauma · 2020Article
- Recommendations for evaluation of bladder and bowel function in pre-clinical spinal cord injury research.The journal of spinal cord medicine · 2020Review
- Potency, efficacy, and selectivity of GR64349 at human recombinant neurokinin NK2 and NK1 receptors.Neuroscience letters · 2019Article
- Prokinetic effects of the neurokinin NK2 receptor agonist [LysNeuropeptides · 2019Article
- Gastrointestinal dysfunction after spinal cord injury.Experimental neurology · 2019Review
- Modulatory effects of intravesical P2X2/3 purinergic receptor inhibition on lower urinary tract electromyographic properties and voiding function of female rats with moderate or severe spinal cord injury.BJU international · 2019Article
- Investigating neurogenic bowel in experimental spinal cord injury: where to begin?Neural regeneration research · 2019Review
- Colorectal and cardiovascular effects of [LysNaunyn-Schmiedeberg's archives of pharmacology · 2018Article
- NK2 and NK1 receptor-mediated effects of NKA and analogs on colon, bladder, and arterial pressure in anesthetized dogs.Naunyn-Schmiedeberg's archives of pharmacology · 2018Article
- Current Knowledge and Novel Frontiers in Lower Urinary Tract Dysfunction after Spinal Cord Injury: Basic Research Perspectives.Urological scienceArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The suitability of various neurokinin-2 (NK2) receptor agonists and routes of administration to elicit on-demand voiding of the bladder and bowel, as future therapy for individuals with spinal cord injury, was examined using a rat model. The current study examined the feasibility of alternative routes of administration, which are more practical for clinical use than intravenous (IV) administration. Voiding and isovolumetric cystometry were recorded in anesthetized, acutely spinalized, female rats after IV, subcutaneous (SC), intramuscular (IM), intranasal (IN), or sublingual (SL) administration of [Lys
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.