Evidence map›Paper›PMID 29237477›Full record

ArticleBMC ophthalmology2017

The impact of glaucoma on quality of life in Ethiopia: a case-control study.

Fisseha A Ayele, Banchamelak Zeraye, Yared Assefa, Kbrom Legesse, Telake Azale, Matthew J Burton

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Vision-Related Quality of Life Among Glaucoma Patients in Saudi Arabia:Sultan Qaboos University medical journal · 2025
    Article
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  10. Seeing through the patient's Eyes: Exploring quality of life in glaucoma patients.Journal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Fisseha A AyeleDepartment of Ophthalmology, School of Medicine, College of Medicine and Health Sciences, University of Gondar, P O Box 196, Gondar, Ethiopia. drfisseha@yahoo.com.
Banchamelak ZerayeDepartment of Ophthalmology, School of Medicine, College of Medicine and Health Sciences, University of Gondar, P O Box 196, Gondar, Ethiopia.
Yared AssefaDepartment of Ophthalmology, School of Medicine, College of Medicine and Health Sciences, University of Gondar, P O Box 196, Gondar, Ethiopia.
Kbrom LegesseDepartment of optometry, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Telake AzaleDepartment of Health Education and Behavioral Sciences, Institute of public health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Matthew J BurtonInternational Centre for Eye Health, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
University of Gondar · ETLondon School of Hygiene & Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlaucoma is a chronic disease characterized by irreversible optic nerve damage and visual field loss that leads to visual impairment and blindness; ultimately limiting personal independence and compromising overall quality of life of affected individuals. There is paucity of information on how glaucoma affects the quality of life of patients in low and middle-income countries where resources for both diagnosis and treatment of such conditions are limited. In this study we investigate the impact of glaucoma on quality of life in Ethiopian patients.

methodsThe quality of life of 307 glaucoma patients and 76 normal controls that were frequency matched to the age and sex profiles of the cases was assessed using Amharic version of Glaucoma Quality of Life -15 questionnaire. Linear regression models and the t-test were employed to compare significant differences in GQL-15 scores and to generate mean and mean differences between cases and controls respectively.

resultsThe mean GQL-15 score in the glaucoma cases was substantially higher (indicating poorer quality of life) than the controls [cases 46.3 (95% CI, 28.8-63.8) and controls 18.6 (95% CI, 15.2-22.0), p < 0.0001]. Cases with normal visual acuity and mild glaucoma had significantly higher scores than the controls. Poorer quality of life was associated with age ≥ 71 years old 51.1 (95%CI, 26.2-75.9), rural residence 55.7 (95%CI, 49.9-61.5), monthly income of <400 Birr (53.1; 95%CI, 50.5-55.6), diagnosis time 1-5 years (49.6; 95%CI, 41.2-57.9), severe visual impairment (70.5; 95%CI, 58.1-82.8), and advanced glaucoma (50.9; 95%CI, 43.6-58.3).

conclusionThese glaucoma patients, including those with normal visual acuity and early disease, had poorer quality of life compared to normal controls. Older age, rural residence, low income and more advanced disease were significantly associated with poorer quality of life. There is a need to increase awareness of the impact of glaucoma among clinicians, patients and their families, for a better understanding of the impact this disease has on a person's life.

Indexed as

Quality of LifeAdultAgedAge FactorsCase-Control StudiesEthiopiaFemaleGlaucomaHumansMaleMiddle AgedRegression AnalysisRural PopulationSickness Impact ProfileSurveys and QuestionnairesVision DisordersEthiopiaGlaucomaGondarGQOL-15Quality of life

Identifiers

PMID29237477
PMCPMC5729503
OpenAlexW2775371053

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.