Evidence map›Paper›PMID 29237419›Full record

ArticleBMC infectious diseases2017

Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children.

Sarah Valerie Schnee, Johannes Pfeil, Clara Marlene Ihling, Julia Tabatabai, Paul Schnitzler

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah Valerie SchneeCenter for Childhood and Adolescent Medicine (General Pediatrics), University Hospital Heidelberg, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany.
Johannes PfeilCenter for Childhood and Adolescent Medicine (General Pediatrics), University Hospital Heidelberg, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany. Johannes.Pfeil@med.uni-heidelberg.de.ORCID 0000-0003-0104-8375
Clara Marlene IhlingGerman Center for Infection Research (DZIF), Heidelberg partner site, Heidelberg, Germany.
Julia TabatabaiCenter for Childhood and Adolescent Medicine (General Pediatrics), University Hospital Heidelberg, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany.
Paul SchnitzlerCenter for Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.
Heidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is the most important cause of severe acute respiratory tract infection in young children. Alere i RSV is a novel molecular rapid test which identifies respiratory syncytial virus in less than 13 min.

methodsWe evaluated the clinical performance of the Alere i RSV assay in a pediatric point-of-care setting during winter season 2016 / 2017. Test results from 518 nasopharyngeal swab samples were compared to a real-time reverse transcription PCR reference standard.

resultsThe overall sensitivity and specificity of the Alere i RSV test assay was 93% (CI

conclusionThe Alere i RSV assay has the potential to facilitate the detection of RSV in pediatric point-of-care settings.

Indexed as

Child, PreschoolFalse Positive ReactionsFemaleHumansInfantInfant, NewbornMaleNasopharynxPoint-of-Care SystemsReagent Kits, DiagnosticReal-Time Polymerase Chain ReactionRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRNA, ViralSensitivity and SpecificityReagent Kits, DiagnosticRNA, Viral

Identifiers

PMID29237419
PMCPMC5729395
OpenAlexW2775526660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.