Evidence map›Paper›PMID 29237413›Full record

ArticleBMC infectious diseases2017

Clinical features of pulmonary cryptococcosis among patients with different levels of peripheral blood CD4

Qian He, Yuan Ding, Wei Zhou, Hongxing Li, Ming Zhang, Yi Shi, Xin Su

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  9. Atypical Radiographic Presentation ofCase reports in infectious diseases · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Qian HeDepartment of Respiratory and Critical Care Medicine, Southern Medical University, Jinling Hospital, Nanjing, 210002, China.
Yuan DingDepartment of Respiratory and Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, China.
Wei ZhouDepartment of Respiratory and Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, China.
Hongxing LiDepartment of Respiratory and Critical Care Medicine, Southern Medical University, Jinling Hospital, Nanjing, 210002, China.
Ming ZhangDepartment of Respiratory Medicine, Third Affiliated Hospital of Soochow University, Changzhou, China.
Yi ShiDepartment of Respiratory and Critical Care Medicine, Southern Medical University, Jinling Hospital, Nanjing, 210002, China.
Xin SuDepartment of Respiratory and Critical Care Medicine, Southern Medical University, Jinling Hospital, Nanjing, 210002, China. suxinjs@163.com.
Nanjing General Hospital of Nanjing Military Command · CNNanjing University · CNSoochow University · CN

Funding

Medical and Health Research Foundation of Nanjing Military Command 12MA082National Key Technology Support Program from Ministry of Science and Technology 2015BAI12B11the National Natural Science Foundation of China 81330035
6 · The paper itself

Abstract

backgroundThe clinical manifestation of pulmonary cryptococcosis varies notably between immunocompromised and immunocompetent patients. To better understand pulmonary cryptococcosis, we compared the clinical features of pulmonary cryptococcosis patients with or without decreased peripheral blood CD4

methodsWe retrospectively reviewed the medical records of 80 patients with cryptococcosis who had been treated in Jingling Hospital from January 2011 to January 2016. According to the normal range of peripheral blood CD4 + T-lymphocyte counts in our population, we chose CD4 = 378/μL as a cut-off value.

resultsThe proportion of fever in the patients with decreased CD4+ T cells was higher than that of the patients with a normal amount of CD4+ T cells (86.7% vs 28.6%, P < 0.001). The incidence of clinical symptoms, such as cough (60.6% vs 64.7%, P = 0.729), chest pain (9.1% vs 26.5%, P = 0.064), and dyspnea (27.3% vs 23.5%, P = 0.725) showed no difference between patients with low CD4

conclusionsCD4

trial registration2011NJKY-023-01. Registered on January 10, 2011.

Indexed as

AdolescentAdultAgedCD4-Positive T-LymphocytesChest PainCoughCryptococcosisDyspneaFemaleHumansImmunocompromised HostLung DiseasesLymphocyte CountMaleMiddle AgedPrognosisCD4+ T cellChest radiographyClinical featurePulmonary cryptococcosis

Identifiers

PMID29237413
PMCPMC5729485
OpenAlexW2774544038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.