Evidence map›Paper›PMID 29237332›Full record

ReviewGlobal public health2019

Traditional, complementary, and alternative medical cures for HIV: rationale and implications for HIV cure research.

Xin Pan, Alice Zhang, Gail E Henderson, Stuart Rennie, Chuncheng Liu, Weiping Cai, Feng Wu, Joseph D Tucker

Abstract readReview
In one paragraph

Review in Global public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xin Pana University of North Carolina Project-China , Guangzhou , People's Republic of China.
Alice Zhanga University of North Carolina Project-China , Guangzhou , People's Republic of China.
Gail E Hendersonc Department of Social Medicine , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Stuart Renniec Department of Social Medicine , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Chuncheng Liua University of North Carolina Project-China , Guangzhou , People's Republic of China.
Weiping Caid Department of Infectious Diseases , Guangzhou Eighth People's Hospital , Guangzhou , People's Republic of China.
Feng Wua University of North Carolina Project-China , Guangzhou , People's Republic of China.
Joseph D Tuckera University of North Carolina Project-China , Guangzhou , People's Republic of China.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Unintended and Intended Implications of HIV Cure: A Social and Ethical AnalysisR01AI108366 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RENNIE, STUART, TUCKER, JOSEPH DAVID · 2013 to 2017
$2.9M
NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI108366
6 · The paper itself

Abstract

Traditional, complementary, and alternative medicine (TCAM) has been used by some people living with HIV (PLHIV) in an attempt to cure HIV. This article reviews the main factors influencing their decision to choose TCAM to cure HIV and discusses implications for HIV cure research. Those who decide to pursue traditional, complementary, and alternative medical cures may be influenced by the health system, cultural, and social dynamics, and their own individual beliefs and preferences. These same factors may impact participation in HIV cure research. People who search for traditional, complementary, and alternative medical cures may face special challenges as they are recruited, consented, and retained within HIV cure research studies. To address these potential challenges, we have suggested solutions focusing on culturally tailored communication and education, formative social science research, and community partnerships with key stakeholders. The social conditions that have promoted traditional, complementary and alternative medical cures will likely impact how PLHIV participate and experience HIV remission trials. Despite the potential challenges, it will be crucial to involve those who have previously sought out traditional cures for HIV in HIV cure research.

Indexed as

Complementary TherapiesMedicine, TraditionalBiomedical ResearchHIV InfectionsHumanscomplementary and alternative medicinecureHIV/AIDSHIV cure researchtraditional medicine

Identifiers

PMID29237332
PMCPMC6092229

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.