Evidence map›Paper›PMID 29236946›Full record

ArticleBrain : a journal of neurology2018

Reply: POLR3A variants in hereditary spastic paraplegia and ataxia.

Martina Minnerop, Delia Kurzwelly, Tim W Rattay, Dagmar Timmann, Holger Hengel, Matthis Synofzik, Claudia Stendel, Rita Horvath, Rebecca Schüle, Alfredo Ramirez

Open access · bronzeAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain : a journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Spinal cord-predominant neuropathology in an adult-onset case of POLR3A-related spastic ataxia.Neuropathology : official journal of the Japanese Society of Neuropathology · 2022
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Martina MinneropInstitute of Neuroscience and Medicine (INM-1), Research Centre Juelich, 52425 Jülich, Germany.
Delia KurzwellyDepartment of Neurology, University of Bonn, 53127 Bonn, Germany.
Tim W RattayCenter for Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
Dagmar TimmannDepartment of Neurology, University of Duisburg-Essen, 45147 Essen, Germany.
Holger HengelCenter for Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
Matthis SynofzikCenter for Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
Claudia StendelDepartment of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-Universität, 80336 Munich, Germany.
Rita HorvathWellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK.
Rebecca SchüleCenter for Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
Alfredo RamirezDepartment of Psychiatry and Psychotherapy, University of Bonn, 53127 Bonn, Germany.
University of Tübingen · DEGerman Center for Neurodegenerative Diseases · DEHertie Institute for Clinical Brain Research · DELudwig-Maximilians-Universität München · DEUniversity of Bonn · DEUniversity of Duisburg-Essen · DEWellcome Centre for Mitochondrial Research · GB

Funding

GENOME STUDIES IN HEREDITARY SPASTIC PARAPLEGIA - beyond the exomeR01NS072248 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Stephan Zuchner · 2011 to 2026
$9.2M
Medical Research Council G1000848Medical Research Council MR/N010035/1Medical Research Council MR/N025431/1Medical Research Council MR/N025431/2NINDS NIH HHS R01 NS072248
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Optic AtrophyHumansIntellectual DisabilityMuscle SpasticityMutationRNA Polymerase IIISpastic Paraplegia, HereditarySpinocerebellar AtaxiasPOLR3A protein, humanRNA Polymerase III

Identifiers

PMID29236946
PMCPMC5837678
OpenAlexW2771335924

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.