Evidence map›Paper›PMID 29236080›Full record

ReviewMolecules (Basel, Switzerland)2017

Three-Dimensional Analysis of the Interactions between hLDH5 and Its Inhibitors.

Giulio Poli, Carlotta Granchi, Mohamed Aissaoui, Filippo Minutolo, Tiziano Tuccinardi

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation.Cellular and molecular life sciences : CMLS · 2022
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Giulio PoliDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. giulio.poli@unisi.it.
Carlotta GranchiDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy. carlotta.granchi@unipi.it.
Mohamed AissaouiDepartment of Chemistry, University of Badji Mokhtar, Sidi Amar-Annaba-B.P. 12, Annaba 23000, Algeria. aissaouimohamed.chem@gmail.com.
Filippo MinutoloDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy. filippo.minutolo@unipi.it.
Tiziano TuccinardiDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy. tiziano.tuccinardi@unipi.it.ORCID 0000-0002-6205-4069
University of Pisa · ITBadji Mokhtar-Annaba University · DZUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibitors of human lactate dehydrogenase (

Indexed as

Antineoplastic AgentsBinding SitesCrystallography, X-RayEnzyme InhibitorsGene ExpressionHumansHydrogen BondingHydrophobic and Hydrophilic InteractionsL-Lactate DehydrogenaseMolecular Docking SimulationNADNeoplasm ProteinsNeoplasmsProtein BindingProtein ConformationProtein Interaction Domains and MotifsAntineoplastic AgentsEnzyme InhibitorsL-Lactate DehydrogenaseNADNeoplasm ProteinsLDH5LDH5 inhibitorsligand–protein interactionsmolecular modeling

Identifiers

PMID29236080
PMCPMC6149858
OpenAlexW2771772275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.