ArticleNature communications2017
Vocal learning promotes patterned inhibitory connectivity.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- Article
- Millisecond-scale motor coding precedes sensorimotor learning in songbirds.bioRxiv : the preprint server for biology · 2024Article
- Disinhibition enables vocal repertoire expansion after a critical period.Nature communications · 2024Article
- Daily singing of adult songbirds functions to maintain song performance independently of auditory feedback and age.Communications biology · 2024Article
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- Cell type specializations of the vocal-motor cortex in songbirds.Cell reports · 2023Article
- ΔCannabis and cannabinoid research · 2023Article
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- Motor cortex analogue neurons in songbirds utilize Kv3 channels to generate ultranarrow spikes.eLife · 2023Article
- Estradiol decreases the excitability of RA projection neurons in adult male zebra finches.Frontiers in cellular neuroscience · 2023Article
- Analogies of human speech and bird song: From vocal learning behavior to its neural basis.Frontiers in psychology · 2023Review
- Performance-Dependent Consolidation of Learned Vocal Changes in Adult Songbirds.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Resurgent NaNature communications · 2021Article
- Extensive GJD2 Expression in the Song Motor Pathway Reveals the Extent of Electrical Synapses in the Songbird Brain.Biology · 2021Article
- Expression of FoxP2 in the basal ganglia regulates vocal motor sequences in the adult songbird.Nature communications · 2021Article
- Cellular transcriptomics reveals evolutionary identities of songbird vocal circuits.Science (New York, N.Y.) · 2021Article
- Article
- Hemispheric asymmetry of calbindin-positive neurons is associated with successful song imitation.Brain research · 2020Article
- Manipulations of inhibition in cortical circuitry differentially affect spectral and temporal features of Bengalese finch song.Journal of neurophysiology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
Skill learning is instantiated by changes to functional connectivity within premotor circuits, but whether the specificity of learning depends on structured changes to inhibitory circuitry remains unclear. We used slice electrophysiology to measure connectivity changes associated with song learning in the avian analog of primary motor cortex (robust nucleus of the arcopallium, RA) in Bengalese Finches. Before song learning, fast-spiking interneurons (FSIs) densely innervated glutamatergic projection neurons (PNs) with apparently random connectivity. After learning, there was a profound reduction in the overall strength and number of inhibitory connections, but this was accompanied by a more than two-fold enrichment in reciprocal FSI-PN connections. Moreover, in singing birds, we found that pharmacological manipulations of RA's inhibitory circuitry drove large shifts in learned vocal features, such as pitch and amplitude, without grossly disrupting the song. Our results indicate that skill learning establishes nonrandom inhibitory connectivity, and implicates this patterning in encoding specific features of learned movements.
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