Evidence map›Paper›PMID 29235061›Full record

ArticleInternational urology and nephrology2018

Differential expression of immune factor between patients with chronic prostatitis/chronic pelvic pain syndrome and the healthy volunteers.

Chen Ye, Guang'an Xiao, Jian Xu, Shengfei Qin, Yuhua Luo, Guanghua Chen, H Henry Lai, Tie Zhou

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Article in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Development of a Novel 11-Gene Signature Related to Immune Subtypes for FibromyalgiaEndocrine, metabolic & immune disorders drug targets · 2026
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  5. Review
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  10. Article
  11. Observational
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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chen YeDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Guang'an XiaoDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Jian XuDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Shengfei QinDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Yuhua LuoDepartment of Urology, Haining People's Hospital, QianJiang West Road, Haining City, ZheJiang Province, People's Republic of China. yuhualuo2015@163.com.
Guanghua ChenDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.
H Henry LaiDivision of Urologic Surgery, Washington University School of Medicine, St Louis, MO, 63110, USA.
Tie ZhouDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China. wenzhoutie80@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImmune mechanisms have been hypothesized to contribute to the development of CP/CPPS. In this study, we investigated the differential expression of immune factors between patients with CP/CPPS and healthy volunteers.

methodsThis study was registered in Australian New Zealand Clinical Trials Registry. Healthy volunteers and patients with CP/CPPS were enrolled in this study. The inclusion criteria for patients were below: (1) aged 18-45 years old; (2) prostatitis-related syndrome longer than 3 months; (3) normal routine urine culture and negative bacterial culture in prostatic fluid. Patients were further classified into two groups: types IIIA and IIIB CP/CPPS according to the results of EPS routine test. Serum immune markers include IgA, IgM, IgG, CD4

resultsThere are total 23 CP/CPPS patients, including 12 type IIIB and 11 type IIIA. Relatively, there are 26 healthy volunteers. The serum levels of IgG were higher in CP/CPPS patients compared to healthy volunteers (1141.2 ± 204.3 vs 1031.9 ± 173.7 mg/L, p = 0.045), while the serum levels of CD8

conclusionsDifferential levels of IgG and CD8

Indexed as

CD4 Lymphocyte CountCD8-Positive T-LymphocytesAdultCase-Control StudiesChronic DiseaseChronic PainHealthy VolunteersHumansImmunoglobulin AImmunoglobulin GImmunoglobulin MImmunoglobulinsMalePelvic PainProstatitisSyndromeImmunoglobulin AImmunoglobulin GImmunoglobulin MImmunoglobulinsChronic pelvic pain syndromeChronic prostatitisImmune

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.