Trial reportSurgical endoscopy2018
Enhanced recovery care versus traditional care after laparoscopic liver resections: a randomized controlled trial.
Trial report in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 9 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Robotic, laparoscopic, and open surgery for perihilar cholangiocarcinoma: a systematic review and direct pairwise meta-analysis.Frontiers in surgery · 2026Pooled it
- Enhanced Recovery After Surgery Guidelines and Hospital Length of Stay, Readmission, Complications, and Mortality: A Meta-Analysis of Randomized Clinical Trials.JAMA network open · 2024Pooled it
- A meta-analysis between robotic hepatectomy and conventional open hepatectomy.Journal of robotic surgery · 2024Pooled it
- Comparing robotic and open surgical techniques in gallbladder cancer management: a detailed systematic review and meta-analysis.Journal of robotic surgery · 2024Pooled it
- The effect of early oral postoperative feeding on the recovery of intestinal motility after gastrointestinal surgery: a systematic review and meta-analysis of randomized clinical trials.Frontiers in nutrition · 2024Pooled it
- Impact of enhanced recovery pathways on patient-reported outcomes after abdominal surgery: a systematic review.Surgical endoscopy · 2023Pooled it
- Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations 2022.World journal of surgery · 2023Pooled it
- Enhanced Recovery Care vs. Traditional Care in Laparoscopic Hepatectomy: A Systematic Review and Meta-Analysis.Frontiers in surgery · 2022Pooled it
- Enhanced Recovery After Surgery (ERAS) Reduces Hospital Costs and Improve Clinical Outcomes in Liver Surgery: a Systematic Review and Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Pooled it
- Article
- Non-placement of nasogastric tube versus early removal of nasogastric tube in the enhanced recovery after surgery of hepatocellular carcinoma: a case control study.Perioperative medicine (London, England) · 2026Article
- Defining benchmarks for postoperative mobilization based on the recommendations of the Enhanced Recovery After Surgery (ERAS) program for liver surgery: a prospective study.Surgical endoscopy · 2025Observational
- Effects of nursing under the enhanced recovery after surgery concept on time to first ambulation after laparoscopic hepatectomy.World journal of gastrointestinal surgery · 2025Article
- Advances in Surgery and Sustainability: The Use of AI Systems and Reusable Devices in Laparoscopic Colorectal Surgery.Cancers · 2025Review
- Optimizing Postoperative Outcomes in Abdominal Surgery: The Role of Enhanced Recovery After Surgery (ERAS) Protocols.Cureus · 2025Article
- Pharmacogenomics of surgical stress response in elective abdominal surgeries.Bioinformation · 2025Article
- Investigating the Effectiveness of Enhanced Recovery after Surgery (ERAS) Protocols in Improving Postoperative Outcomes and Reducing Hospital Readmission Rates in Patients Undergoing abdominal Surgery.Journal of pharmacy & bioallied sciences · 2024Article
- Promoting application of enhanced recovery after surgery protocols during perioperative localized abdominal and thoracic neuroblastomas.Pediatric surgery international · 2024Article
- Implementation of an ERAS protocol on cirrhotic patients in liver resection: a cohort study.Updates in surgery · 2024Observational
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnhanced recovery after surgery (ERAS), with several evidence-based elements, has been shown to shorten length of hospital stay and reduce perioperative hospital costs in many operations. This randomized clinical trial was performed to compare complications and hospital stay of laparoscopic liver resection between ERAS and traditional care.
methodsA randomized controlled trial was performed for laparoscopic liver resection from August 2015 to August 2016. Patients were randomly divided into ERAS group and traditional care group. The primary outcome was length of hospital stay (LOS) after surgery. Second outcomes included postoperative complications, hospital cost, and 30-day readmissions. Elements used in ERAS group included more perioperative education, nurse navigators, nutrition support for liver diseases, respiratory therapy, oral carbohydrate 2 h before operation, early mobilization and oral intake, goal-directed fluid therapy, less drainages, postoperative nausea and vomiting (PONV) prophylaxis and multimodal analgesia.
resultsThe study included 58 (two conversion to laparotomy) patients in ERAS group and 61 (three conversion to laparotomy) patients in the traditional care group. Postoperative LOS was significantly shorter in the ERAS group than traditional care group (5 vs. 8 days; p < 0.001). ERAS program significantly reduced the hospital costs (CNY 45413.1 vs. 55794.1; p = 0.006) and complications (36.2 vs. 55.7%; p = 0.033). Duration till first flatus and PONV were significantly reduced in ERAS group. Pain control was better in ERAS (Visual analogue scale (VAS) POD1 (≥ 4) 19.0 vs. 39.3%, p = 0.017; VAS POD1 2.5 vs. 3.1, p = 0.010). There was no difference in the rate of 30-day readmissions (6.9 vs. 8.2%; p = 1.000).
conclusionERAS protocol is feasible and safe for laparoscopic liver resection. Patients in ERAS group have less pain and complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.