ArticleEuropean journal of applied physiology2018
Do acute effects of exercise on vascular function predict adaptation to training?
Article in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04371757 (Influence of the Autonomic Nervous System on Endothelial Function as an Acute Response to Exercise in Hypertensive Individuals), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of the Autonomic Nervous System on Endothelial Function as an Acute Response to Exercise in Hypertensive Individuals: a Randomized Double-blind Protocol Study
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- What is the impact of aerobic fitness and movement interventions on low-flow-mediated vasoconstriction? A systematic review of observational and intervention studies.Vascular medicine (London, England) · 2022Pooled it
- Acute effect of lower-limb peristaltic pulse external pneumatic compression on segmental arterial stiffness in healthy young adults.Physiological reports · 2025Trial
- Post-isometric exercise hypotension occurs irrespective of muscle mass in adults with hypertension: A randomized clinical trial.Clinics (Sao Paulo, Brazil) · 2025Trial
- The acute effect of passively assisted trunk stretching on central arterial stiffness and blood pressure in middle-aged to older adults.European journal of applied physiology · 2024Trial
- Impact of supra-maximal interval training vs. high-intensity interval training on cardiac auto-regulation response in physically active adults.European journal of applied physiology · 2024Trial
- The acute effects of exercise intensity and inorganic nitrate supplementation on vascular health in females after menopause.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Trial
- Individuals with controlled hypertension show endothelial integrity following a bout of moderate-intensity exercise: randomized clinical trial.Scientific reports · 2021Trial
- Aerobic exercise, but not isometric handgrip exercise, improves endothelial function and arterial stiffness in patients with myocardial infarction undergoing coronary intervention: a randomized pilot study.BMC cardiovascular disorders · 2021Trial
- Effects of resveratrol or estradiol on postexercise endothelial function in estrogen-deficient postmenopausal women.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Trial
- Acute effects of moderate-intensity continuous and high-intensity interval exercise on vascular function.European journal of applied physiology · 2026Article
- The impact of a 12-week high-intensity interval training program on popliteal vascular responses to prolonged sitting.European journal of applied physiology · 2026Article
- Acute measurement of flow-mediated dilation following passive heating in adults: The confounding role of altered shear stress and baseline vasodilation.Physiological reports · 2026Article
- Vascular function responses to resistance exercise followed by intermittent hypoxic exposure in untrained males.European journal of applied physiology · 2026Article
- Low-Load Blood Flow Restriction Training Enhances Brachial Blood Flow During Exercise but not Reactive Hyperemia in Experienced Climbers.Scandinavian journal of medicine & science in sports · 2026Article
- Day-to-Day Reproducibility of Arterial Stiffness Following a Bout of Resistance Exercise in Healthy Young Females: A Reliability Study.Health science reports · 2026Article
- The Impact of Obesity on Endothelial Function Following Maximal Aerobic Exercise.International journal of exercise science · 2026Article
- Optimizing cerebrovascular endothelial health through shear stress modulation.Experimental physiology · 2025Review
- Impact of acute and chronic cycling exercise on microvascular reactivity of the upper and lower extremity muscles in young healthy females.Journal of exercise science and fitness · 2025Article
- Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults.Experimental physiology · 2025Article
- Vascular function after acute aerobic exercise in adults with and without type 2 diabetes mellitus.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 4 countries.
Funding
Abstract
purposeNo previous study has explored the importance of exercise-induced changes in vascular function to prolonged adaptations. Therefore, the purpose was to explore the within-subject relationship between the acute post-exercise change in brachial artery endothelial function (flow-mediated dilation, FMD) and the change in resting FMD after a 2-week exercise training in healthy volunteers.
methodsTwenty one healthy, young men (24 ± 5 years) underwent assessment of brachial artery FMD using high-resolution ultrasound before and after 30-min of moderate-intensity cycle exercise (80% maximal heart rate). Subsequently, subjects performed five 30-min cycle exercise bouts at 80% maximal heart rate across a 2-week period, followed by repeat assessment of resting brachial FMD post-training.
resultsCorrecting for changes in diameter and shear, FMD did not change after the initial exercise bout (P = 0.26). However, a significant correlation was found between post-exercise changes in FMD and adaptation in resting FMD after training (r = 0.634, P = 0.002), where an acute decrease in post-exercise FMD resulted in a decrease in baseline FMD after 2 weeks and vice versa. We also found a positive correlation between antegrade shear rate during exercise and change in FMD% after acute exercise and after exercise training (r = 0.529 and 0.475, both P < 0.05).
conclusionOur findings suggest that acute post-exercise changes in vascular function are related to changes in resting FMD after a 2-week endurance exercise training period in healthy men, an effect that may be related to exercise-induced increases in antegrade shear rate. This provides further insight into the relevance of acute changes in shear and FMD for subsequent adaptation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.