Evidence map›Paper›PMID 29234685›Full record

ArticleJournal of immunology research2017

Local and Systemic CD4

Charlene Hawkins, Guzel Shaginurova, D Auriel Shelton, Jose D Herazo-Maya, Kyra A Oswald-Richter, Joseph E Rotsinger, Anjuli Young, Lindsay J Celada, Naftali Kaminski, Carla Sevin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Declining Pulmonary Function in Interstitial Lung Disease Linked to Lymphocyte Dysfunction.American journal of respiratory and critical care medicine · 2020
    Pooled it
  2. HLA-DRRespiratory research · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Increased proportions of circulating PD-1Respiratory research · 2024
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. The Role ofMicroorganisms · 2022
    Review
  16. Innate and Adaptive Immunity in Noninfectious Granulomatous Lung Disease.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Charlene HawkinsDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.
Guzel ShaginurovaDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.
D Auriel SheltonDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.
Jose D Herazo-MayaSection of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT 06520, USA.
Kyra A Oswald-RichterDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.
Joseph E RotsingerDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.ORCID 0000-0002-5046-2102
Anjuli YoungDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.
Lindsay J CeladaDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.
Naftali KaminskiSection of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT 06520, USA.
Carla SevinDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.
Wonder P DrakeDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2363, USA.ORCID 0000-0001-9406-3130
Vanderbilt University · USYale University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Sarcoidosis and A1AT Genomics & Informatics CenterU01HL112707 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECICH, MICHAEL JOHN, KAMINSKI, NAFTALI · 2012 to 2015
$8.5M
Immunobiology of Blood and Vascular Systems Training ProgramT32HL069765 · NHLBI · VANDERBILT UNIVERSITY · PI HAWIGER, JACK J · 2002 to 2016
$6.5M
Interdisciplinary Training Program in Lung ResearchT32HL094296 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ray Stokes Peebles · 2008 to 2026
$6.3M
Microbial induction of sarcoidosis CD4+ T cell dysfunctionR01HL117074 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL, DRAKE, WONDER P. · 2013 to 2017
$3.8M
Mentoring in Translational Research in Interstitial Lung DiseasesK24HL127301 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Wonder P. Drake · 2016 to 2026
$1.2M
The Role of CD8 T Cells in Chronic Granulomatous InflammationK01HL103179 · NHLBI · VANDERBILT UNIVERSITY · PI OSWALD-RICHTER, KYRA A. · 2010 to 2014
$561k
Investigation of microbial hetergeneity to sarcoidosis and AAT clinical outcomeU01HL112694 · NHLBI · VANDERBILT UNIVERSITY · PI DRAKE, WONDER P. · 2012 to 2014
$463k
NCATS NIH HHS UL1 TR002243NCI NIH HHS P30 CA068485NCRR NIH HHS UL1 RR024975NHLBI NIH HHS K01 HL103179NHLBI NIH HHS K24 HL127301NHLBI NIH HHS R01 HL117074NHLBI NIH HHS T32 HL069765NHLBI NIH HHS T32 HL094296NHLBI NIH HHS U01 HL112694NHLBI NIH HHS U01 HL112707NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

Investigation of the Th1 immune response in sarcoidosis CD4

Indexed as

AdultAgedApoptosisCD4-Positive T-LymphocytesCell ProliferationCells, CulturedClonal AnergyCytokinesDisease ProgressionFemaleGene Expression RegulationHumansLymphocyte ActivationMaleMiddle AgedProgrammed Cell Death 1 ReceptorCytokinesPDCD1 protein, humanProgrammed Cell Death 1 ReceptorReceptors, Antigen, T-Cell, alpha-beta

Identifiers

PMID29234685
PMCPMC5695030
OpenAlexW2767384949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.