Evidence map›Paper›PMID 29234670›Full record

ArticleMicrobial cell (Graz, Austria)2017

Mitochondrial energy metabolism is required for lifespan extension by the spastic paraplegia-associated protein spartin.

Julia Ring, Patrick Rockenfeller, Claudia Abraham, Jelena Tadic, Michael Poglitsch, Katherina Schimmel, Julia Westermayer, Simon Schauer, Bettina Achleitner, Christa Schimpel and 8 more

Open access · goldAbstract read
In one paragraph

Article in Microbial cell (Graz, Austria), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Anti-ageing effects of red ginseng on female Drosophila melanogaster.Journal of cellular and molecular medicine · 2020
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 5 countries.

Julia RingInstitute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Patrick RockenfellerBioTechMed Graz, Graz, Austria.
Claudia AbrahamBioTechMed Graz, Graz, Austria.
Jelena TadicBioTechMed Graz, Graz, Austria.
Michael PoglitschBioTechMed Graz, Graz, Austria.
Katherina SchimmelBioTechMed Graz, Graz, Austria.
Julia WestermayerBioTechMed Graz, Graz, Austria.
Simon SchauerBioTechMed Graz, Graz, Austria.
Bettina AchleitnerBioTechMed Graz, Graz, Austria.
Christa SchimpelBioTechMed Graz, Graz, Austria.
Barbara MoitziBioTechMed Graz, Graz, Austria.
Gerald N RechbergerBioTechMed Graz, Graz, Austria.
Stephan J SigristBioTechMed Graz, Graz, Austria.
Didac Carmona-GutierrezBioTechMed Graz, Graz, Austria.
Guido KroemerBioTechMed Graz, Graz, Austria.
Sabrina BüttnerBioTechMed Graz, Graz, Austria.
Tobias EisenbergBioTechMed Graz, Graz, Austria.
Frank MadeoBioTechMed Graz, Graz, Austria.
University of Graz · ATNawi Graz · ATBioTechMed-Graz · ATCharité - Universitätsmedizin Berlin · DEStockholm University · SE

Funding

Austrian Science Fund FWF P 27183Austrian Science Fund FWF P 27893Austrian Science Fund FWF P 29203Austrian Science Fund FWF P 29262Austrian Science Fund FWF W 1226
6 · The paper itself

Abstract

Hereditary spastic paraplegias, a group of neurodegenerative disorders, can be caused by loss-of-function mutations in the protein spartin. However, the physiological role of spartin remains largely elusive. Here we show that heterologous expression of human or

Indexed as

agingcell deathmetabolismmitochondriapyruvate dehydrogenaserespirationSPG20

Identifiers

PMID29234670
PMCPMC5722644
OpenAlexW2774686915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.