ReviewFrontiers in molecular biosciences2017
A Matter of Taste: Lineage-Specific Loss of Function of Taste Receptor Genes in Vertebrates.
Review in Frontiers in molecular biosciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Relaxation of selective constraint on the sweet-taste receptor gene TAS1R2 in lorisiform primates.Scientific reports · 2025Article
- Synchronized Expansion and Contraction of Olfactory, Vomeronasal, and Taste Receptor Gene Families in Hystricomorph Rodents.Molecular biology and evolution · 2024Article
- Diversity and evolution of the vertebrate chemoreceptor gene repertoire.Nature communications · 2024Article
- A vertebrate-wide catalogue of T1R receptors reveals diversity in taste perception.Nature ecology & evolution · 2024Article
- A singular shark bitter taste receptor provides insights into the evolution of bitter taste perception.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Evolutionary constraint and innovation across hundreds of placental mammals.Science (New York, N.Y.) · 2023Article
- Article
- Bitter taste receptors of the zebra finch (Frontiers in physiology · 2023Article
- Evolutionary insights into umami, sweet, and bitter taste receptors in amphibians.Ecology and evolution · 2021Article
- Understanding the evolution of nutritive taste in animals: Insights from biological stoichiometry and nutritional geometry.Ecology and evolution · 2021Review
- Seed dispersers shape the pulp nutrients of fleshy-fruited plants.Proceedings. Biological sciences · 2021Article
- Alteration, Reduction and Taste Loss: Main Causes and Potential Implications on Dietary Habits.Nutrients · 2020Review
- Insights into the Function and Evolution of Taste 1 Receptor Gene Family in the Carnivore Fish Gilthead Seabream (International journal of molecular sciences · 2020Article
- Expression of Taste Receptor 2 Subtypes in Human Testis and Sperm.Journal of clinical medicine · 2020Article
- Taste Perception of Antidesma bunius Fruit and Its Relationships to Bitter Taste Receptor Gene Haplotypes.Chemical senses · 2018Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vertebrates can perceive at least five different taste qualities, each of which is thought to have a specific role in the evolution of different species. The avoidance of potentially poisonous foods, which are generally bitter or sour tasting, and the search for more nutritious ones, those with high-fat and high-sugar content, are two of the most well-known examples. The study of taste genes encoding receptors that recognize ligands triggering taste sensations has helped to reconstruct several evolutionary adaptations to dietary changes. In addition, an increasing number of studies have focused on pseudogenes, genomic DNA sequences that have traditionally been considered defunct relatives of functional genes mostly because of the presence of deleterious mutations interrupting their open reading frames. The study of taste receptor pseudogenes has helped to shed light on how the evolutionary history of taste in vertebrates has been the result of a succession of gene gain and loss processes. This dynamic role in evolution has been explained by the "less-is-more" hypothesis, suggesting gene loss as a mechanism of evolutionary change in response to a dietary shift. This mini-review aims at depicting the major lineage-specific loss of function of taste receptor genes in vertebrates, stressing their evolutionary importance and recapitulating signatures of natural selection and their correlations with food habits.
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