Evidence map›Paper›PMID 29234655›Full record

ArticleRevista brasileira de ortopedia

Characterization, survival analysis, and expression of IGFR in tumor samples from patients diagnosed with Ewing family tumors treated at the Barretos Cancer Hospital.

Adriano Jander Ferreira, Erica Boldrini, Rossana Verónica Mendoza López, Cristovam Scapulatempo Neto, Julie Francine Cerutti Santos, Luiz Fernando Lopes

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista brasileira de ortopedia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adriano Jander FerreiraUniversidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil.
Erica BoldriniHospital de Câncer Infanto-Juvenil de Barretos, Oncologia Pediátrica, Barretos, SP, Brazil.
Rossana Verónica Mendoza LópezHospital de Câncer de Barretos, Barretos, SP, Brazil.
Cristovam Scapulatempo NetoHospital de Câncer de Barretos, Barretos, SP, Brazil.
Julie Francine Cerutti SantosHospital de Câncer de Barretos, Barretos, SP, Brazil.
Luiz Fernando LopesHospital de Câncer Infanto-Juvenil de Barretos, Oncologia Pediátrica, Barretos, SP, Brazil.
Hospital de Câncer de Barretos · BRUniversidade Federal do Triângulo Mineiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesStudy the clinical characteristics of patients diagnosed with Ewing family tumors (EFTs) and survival analysis based on risk criteria and expression of the surface protein known as insulin-like growth factor (IGFR).

methodsThis was a retrospective cohort study based on clinical data from 77 patients diagnosed with EFTs treated by the Department of Pediatric Oncology at the Barretos Cancer Hospital in a period between 2003 and 2012. Biological samples of patients were examined for the presence of the surface receptor IGFR.

resultsThe overall survival rate (OSR) of patients included in the study was 45% at five years, and EFS was 30% at five years. Metastasis at diagnosis was present in 44.2% of the sample; 88.2% of the sample was male (

conclusionsThese results showed a higher incidence of metastasis at diagnosis in patients with EFTs treated at the Barretos Cancer Hospital (BCH). Extrapulmonary metastases were a negative prognostic factor in this study. Surgical treatment of the primary tumor was a factor for better prognosis. Strong expression of IGFR was more frequent in patients with metastases at diagnosis, but did not represent a prognostic factor for EFTs.

Indexed as

Bone neoplasmsEwingInsulin-like growth factor INeuroectodermal tumorsOncologyPeripheralPrimitiveSarcomaSurvival analysis

Identifiers

PMID29234655
PMCPMC5720841
OpenAlexW2566125084

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.