Evidence map›Paper›PMID 29234638›Full record

ArticleLiver cancer2017

Prospective Comparison of Gd-EOB-DTPA-Enhanced MRI with Dynamic CT for Detecting Recurrence of HCC after Radiofrequency Ablation.

Yasuharu Imai, Kazuhiro Katayama, Masatoshi Hori, Takayuki Yakushijin, Kenji Fujimoto, Toshifumi Itoh, Takumi Igura, Mitsuru Sakakibara, Manabu Takamura, Masakatsu Tsurusaki and 8 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Liver cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Predicting liver ablation volumes with real-time MRI thermometry.JHEP reports : innovation in hepatology · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Evaluation and Prediction of Treatment Response for Hepatocellular Carcinoma.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Article
  12. [The consensus on tertiary prevention of primary liver cancer (2022 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Yasuharu ImaiDepartment of Gastroenterology, Ikeda Municipal Hospital, Ikeda, Japan.
Kazuhiro KatayamaDepartment of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan.
Masatoshi HoriDepartment of Radiology, Osaka University Graduate School of Medicine, Suita, Japan.
Takayuki YakushijinDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Kenji FujimotoDepartment of Internal Medicine, National Hospital Organization Minamiwakayama Medical Center, Tanabe, Japan.
Toshifumi ItohDepartment of Gastroenterology and Hepatology, JCHO Osaka Hospital, Osaka, Japan.
Takumi IguraDepartment of Gastroenterology, Ikeda Municipal Hospital, Ikeda, Japan.
Mitsuru SakakibaraDepartment of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan.
Manabu TakamuraDepartment of Radiology, Ikeda Municipal Hospital, Ikeda, Japan.
Masakatsu TsurusakiDepartment of Radiology, Faculty of Medicine, Kindai University, Sayama, Japan.
Hiroto TakahashiDepartment of Radiology, Osaka University Graduate School of Medicine, Suita, Japan.
Katsuyuki NakanishiDepartment of Diagnostic Radiology, Osaka International Cancer Institute, Osaka, Japan.
Noriaki UsukiDepartment of Radiology, JCHO Osaka Hospital, Osaka, Japan.
Koh TsujiDepartment of Radiology, National Hospital Organization Minamiwakayama Medical Center, Tanabe, Japan.
Hiroshi OhashiDepartment of Pathology, Ikeda Municipal Hospital, Ikeda, Japan.
Tonsok KimDepartment of Radiology, Osaka University Graduate School of Medicine, Suita, Japan.
Tetsuo TakeharaDepartment of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Takamichi MurakamiDepartment of Radiology, Faculty of Medicine, Kindai University, Sayama, Japan.
Osaka University · JPIkeda Municipal Hospital · JPOsaka Medical Center for Cancer and Cardiovascular Diseases · JPKindai University · JPOsaka Hospital · JPMinami Wakayama Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe prospectively compared the efficacy of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) with that of dynamic multidetector computed tomography (MDCT) for detection of recurrent hypervascular hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA).

methodsInstitutional review board approval and written informed consent were obtained for this multicenter study. Ninety-seven HCC patients treated with curative RFA underwent both Gd-EOB-DTPA-enhanced MRI and dynamic MDCT every 3-4 months. HCC diagnosis was made based on the typical enhancement pattern of HCC on MRI and/or CT by on-site consensus reading. Two blinded observers independently assessed image datasets to compare diagnostic accuracy, sensitivity, specificity, and the areas under the receiver operating characteristic curve (AUROC).

resultsRecurrence was observed in 48 of 97 patients. Among these, 22 were diagnosed by both Gd-EOB-DTPA-enhanced MRI and MDCT; the remainder were diagnosed by only one of these 2 modalities. Recurrence was diagnosed in more patients by Gd-EOB-DTPA-enhanced MRI than by MDCT (44 vs. 26 patients,

conclusionsCompared with dynamic MDCT, Gd-EOB-DTPA-enhanced MRI had higher diagnostic accuracy and sensitivity for detection of recurrent hypervascular HCC and may be a better tool for following patients after RFA.

Indexed as

Computed tomographyGd-EOB-DTPA-MRIHepatocellular carcinomaRadiofrequency ablationRecurrence

Identifiers

PMID29234638
PMCPMC5704682
OpenAlexW2765873591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.