Evidence map›Paper›PMID 29234623›Full record

ArticleEuropean thyroid journal2017

Are Perinatal Events Risk Factors for Childhood Thyroid Autoimmunity?

Berglind Jonsdottir, Markus Lundgren, Sara Wallengren, Åke Lernmark, Ida Jönsson, Helena Elding Larsson, DiPiS Study Group

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European thyroid journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 13 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Berglind JonsdottirDepartment of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.
Markus LundgrenDepartment of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.
Sara WallengrenDepartment of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.
Åke LernmarkDepartment of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.
Ida JönssonDepartment of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.
Helena Elding LarssonDepartment of Clinical Sciences, Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.
DiPiS Study Group
Lund University · SESkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnvironmental and genetic factors possibly trigger thyroid autoimmunity. Studies on perinatal risk factors for childhood thyroid autoimmunity are sparse.

objectivesThe aim was to investigate if perinatal factors, family history of autoimmune diseases, and

methodsSamples from 1,874 ten-year-old children were analyzed for autoantibodies to thyroid peroxidase (TPOAb), thyroglobulin (TGAb), and

resultsThyroid autoimmunity was found in 6.9% of the children (TPOAb 4.4%, TGAb 5.8%, both autoantibodies 3.3%) and was overrepresented in girls. Prematurity was positively related to TGAb (OR: 2.4,

conclusionsThyroid autoimmunity was found in 6.9% of the 10-year-old children who were being followed for their risk of type 1 diabetes. No relation to perinatal factors was found, with the exception of a possible association between prematurity and TGAb. Family history of autoimmune diseases increased the risk of thyroid autoimmunity.

Indexed as

Childhood thyroid autoimmunityHLA-DQ genotypesPerinatal and hereditary risk factorsThyroglobulin autoantibodiesThyroid peroxidase autoantibodies

Identifiers

PMID29234623
PMCPMC5704722
OpenAlexW2754159496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.