ArticlePhotoacoustics2018
The characterization of an economic and portable LED-based photoacoustic imaging system to facilitate molecular imaging.
Article in Photoacoustics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.
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Who cites it
85 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Noninvasive hemoglobin sensing and imaging: optical tools for disease diagnosis.Journal of biomedical optics · 2022Pooled it
- Advanced methods of wearable ultrasound and photoacoustic imaging devices: A review.Photoacoustics · 2026Article
- Optimization of light source parameters for photoacoustic imaging: trade-offs, technologies, and clinical considerations.JPhys photonics · 2026Review
- High frequency miniaturized transducer for facial and lingual full-mouth human imaging including third molars.Biomedical optics express · 2026Article
- Efficient denoising in LED-based optoacoustic tomography with squeeze-and-excitation deep convolutional networks.Journal of biomedical optics · 2026Article
- Near-infrared-II pulsed laser diode array for spectral photoacoustic imaging of deep tissue oxygenation.Biomedical optics express · 2025Article
- Clinical translation of photoacoustic imaging using exogenous molecular contrast agents [Invited].Biomedical optics express · 2025Review
- Performance characterization of light-emitting diode array-based photoacoustic computed tomography (LED-PACT).Biomedical optics express · 2025Article
- Activatable Photoacoustic Probe for Imaging Infection: Gold Nanorod Dissociation In Vivo Reports Bacterial Protease Activity.ACS nano · 2025Article
- LED-based optoacoustic tomography of mice.Journal of biomedical optics · 2025Article
- Cost-Effective Photoacoustic Imaging Using High-Power Light-Emitting Diodes Driven by an Avalanche Oscillator.Sensors (Basel, Switzerland) · 2025Article
- Advances in Portable Optical Microscopy Using Cloud Technologies and Artificial Intelligence for Medical Applications.Sensors (Basel, Switzerland) · 2024Review
- Tri-modalityPhotoacoustics · 2024Article
- Multiwavelength laser diode based portable photoacoustic and ultrasound imaging system for point of care applications.Journal of biophotonics · 2024Article
- U-Net enhanced real-time LED-based photoacoustic imaging.Journal of biophotonics · 2024Article
- Dual-modal Photoacoustic and Ultrasound Imaging: from preclinical to clinical applications.Frontiers in photonics · 2024Article
- Review of Deep Learning Approaches for Interleaved Photoacoustic and Ultrasound (PAUS) Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- Assembly of fluorophore J-aggregates with nanospacer onto mesoporous nanoparticles for enhanced photoacoustic imaging.Photoacoustics · 2023Article
- Article
- Noninvasive measurement of local temperature using ultrasound-switchable fluorescence.Biomedical optics express · 2023Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Photoacoustic imaging (PAI) is a non-invasive, high-resolution hybrid imaging modality that combines optical excitation and ultrasound detection. PAI can image endogenous chromophores (melanin, hemoglobin, etc.) and exogenous contrast agents in different medical applications. However, most current equipment uses sophisticated and complicated OPO lasers with tuning and stability features inconsistent with broad clinical deployment. As the number of applications of PAI in medicine increases, there is an urgent need to make the imaging equipment more compact, portable, and affordable. Here, portable light emitting diode - based photoacoustic imaging (PLED-PAI) was introduced and characterized in terms of system specifications, light source characterizations, photoacoustic spatial/temporal resolution, and penetration. The system uses two LED arrays attached to the sides of a conventional ultrasound transducer. The LED pulse repetition rate is tunable between 1 K Hz, 2 K Hz, 3 K Hz, and 4 K Hz. The axial resolution was 0.268 mm, and the lateral resolution was between 0.55 and 0.59 mm. The system could detect optical absorber (pencil lead) at a depth of 3.2 cm and the detection limits of indocyanine green (ICG) and methylene blue (MB) were 9 μM and 0.78 mM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.