Evidence map›Paper›PMID 29234538›Full record

ArticleArab journal of urology2017

Can androgen-deprivation therapy obviate the need of channel transurethral resection of the prostate in advanced prostate cancer with urinary retention? A prospective study.

Rajeev Sood, Ritesh Kumar Singh, Hemant Goel, T Manasa, Nikhil Khattar, Mahesh C Tripathi

Open access · diamondAbstract read
In one paragraph

Article in Arab journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rajeev SoodDepartment of Urology, Post-Graduate Institute of Medical Education and Research (PGIMER), Dr. Ram Manohar Lohia (RML) Hospital, New Delhi, Delhi, India.
Ritesh Kumar SinghDepartment of Urology, Post-Graduate Institute of Medical Education and Research (PGIMER), Dr. Ram Manohar Lohia (RML) Hospital, New Delhi, Delhi, India.
Hemant GoelDepartment of Urology, Post-Graduate Institute of Medical Education and Research (PGIMER), Dr. Ram Manohar Lohia (RML) Hospital, New Delhi, Delhi, India.
T ManasaDepartment of Urology, Post-Graduate Institute of Medical Education and Research (PGIMER), Dr. Ram Manohar Lohia (RML) Hospital, New Delhi, Delhi, India.
Nikhil KhattarDepartment of Urology, Post-Graduate Institute of Medical Education and Research (PGIMER), Dr. Ram Manohar Lohia (RML) Hospital, New Delhi, Delhi, India.
Mahesh C TripathiDepartment of Urology, Post-Graduate Institute of Medical Education and Research (PGIMER), Dr. Ram Manohar Lohia (RML) Hospital, New Delhi, Delhi, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficacy of androgen-deprivation therapy (ADT) in relieving urinary retention in patients with advanced prostate cancer presenting with urinary retention or a high post-void residual urine volume (PVR). PATIENTS AND

methodsPatients with advanced prostate cancer with an indwelling catheter for acute/chronic urinary retention, or with a high PVR (>200 mL) who had not received any previous treatment were included in the study. Patients with localised prostate cancer eligible for receiving any therapy aimed at cure were excluded. All enrolled patients were managed by ADT (LHRH antagonist/agonist or orchidectomy) combined with α-adrenoceptor antagonist/combined therapy for at least 1 month to a maximum of 3 months; they were given their first trial of voiding without catheter after 1 month, and monthly thereafter.

resultsA total of 101 patients received ADT of which 97 were able to void successfully at the end of 3 months. In all, 27 patients could void in the first month, followed by 50 in the second month, and an additional 20 in the third month. There was a significant decrease in prostate volume, PVR, and International Prostate Symptom Score, and maximum urinary flow rates improved with normalisation of renal functions and resolution of upper tract changes noted on ultrasonography.

conclusionADT can relieve retention and decrease PVR over a period of time obviating the need for channel transurethral resection of the prostate.

Indexed as

ADTADT, androgen-deprivation therapyADT in retentionAUR, acute urinary retentionProstate cancerpTURP, palliative TURPTWOC, trial of voiding without catheterUSG KUB, ultrasonography of the kidney, ureter and bladder

Identifiers

PMID29234538
PMCPMC5717466
OpenAlexW2765242973

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.