Evidence map›Paper›PMID 29234530›Full record

ArticleArab journal of urology2017

A prospective randomised double-blind placebo-controlled trial to assess the effect of diuretics on shockwave lithotripsy of calculi.

Sagar Sabharwal, L Jeyaseelan, Arabind Panda, Lionel Gnanaraj, Nitin S Kekre, Antony Devasia

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Arab journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05270421 (Effect of Furosemide on Outcome of Extracorporeal Shock Wave Lithotripsy for Renal and Ureteral Calculi; a Randomized, Triple-blinded, Controlled Trial), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05270421 phase3unknown statusnot on this mapstarted 2020, after this paper: background citation

Effect of Furosemide on Outcome of Extracorporeal Shock Wave Lithotripsy for Renal and Ureteral Calculi; a Randomized, Triple-blinded, Controlled Trial

TypeinterventionalSponsorShiraz University of Medical SciencesRan2020 to 2022Enrolled500ConditionsUrolithiasis, Nephrolithiasis, Urinary Calculi, UreterolithiasisArmsFurosemide 40 mg, Conventional Treatment
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The effects of pretreatment oral hydration on extracorporeal shockwave lithotripsy outcomes A randomized controlled trial.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sagar SabharwalDepartment of Urology, Christian Medical College, Vellore, Tamil Nadu, India.
L JeyaseelanDepartment of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.
Arabind PandaDepartment of Urology, Christian Medical College, Vellore, Tamil Nadu, India.
Lionel GnanarajDepartment of Urology, Christian Medical College, Vellore, Tamil Nadu, India.
Nitin S KekreDepartment of Urology, Christian Medical College, Vellore, Tamil Nadu, India.
Antony DevasiaDepartment of Urology, Christian Medical College, Vellore, Tamil Nadu, India.
Christian Medical College · INChristian Medical College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effect of diuretics with shockwave lithotripsy (SWL) on the treatment of renal and upper ureteric calculi. PATIENTS AND

methodsAdult patients with a solitary non-obstructive radio-opaque renal or upper ureteric calculus with normal renal function were included. They were prospectively randomised to receive either SWL with placebo or SWL with diuretics (40 mg parenteral furosemide) in a double-blind manner with a sample size of 48 patients in each arm. The primary outcomes were the SWL success and failure rates. The secondary outcomes were the number of shocks and sessions.

resultsComplete fragmentation was achieved in 89.6% of the patients in the furosemide arm as compared to 81.3% in the placebo arm. Clearance was achieved in 77.1% of the patients in the furosemide arm as compared to 70.8% in the placebo arm. The number of shocks and the number of sessions were higher in the placebo arm. These differences were not statistically significant.

conclusionThe use of diuretics along with SWL treatment of renal and upper ureteric calculi does not show a statistically significant improvement in fragmentation or clearance.

Indexed as

DiureticsPCNL, percutaneous nephrolithotomyRenal calculiRIRS, retrograde intrarenal surgeryShockwave lithotripsySWL, shockwave lithotripsyUreteric calculiURS, ureterorenoscopy

Identifiers

PMID29234530
PMCPMC5717457
OpenAlexW2730950709

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.