Evidence map›Paper›PMID 29234446›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2017

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin.

Angel Josabad Alonso-Castro, Fabiola Domínguez, Alan Joel Ruiz-Padilla, Nimsi Campos-Xolalpa, Juan Ramón Zapata-Morales, Candy Carranza-Alvarez, Juan Jose Maldonado-Miranda

Abstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biological Activities of Organic Extracts of the GenusMolecules (Basel, Switzerland) · 2022
    Pooled it
  2. Phytochemical Characterization and Toxicity Activity ofMolecules (Basel, Switzerland) · 2026
    Article
  3. Phytochemistry and Pharmacological Potential of the GenusPharmaceuticals (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. A perspective review on factors that influence mutagenicity in medicinal plants and their health implications.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Review
  7. Review
  8. Antiparasitic Activity of Isolated Fractions fromAntibiotics (Basel, Switzerland) · 2024
    Article
  9. Neuropharmacological Activities ofPharmaceuticals (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Saudi journal of biological sciences · 2021
    Article
  13. Study of the Properties of In VitroPlants (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angel Josabad Alonso-CastroDepartamento de Farmacia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, GTO, Mexico.ORCID 0000-0003-2660-8156
Fabiola DomínguezCentro de Investigación Biomédica de Oriente, Instituto Mexicano del Seguro Social, Metepec, PUE, Mexico.ORCID 0000-0001-8854-7083
Alan Joel Ruiz-PadillaDepartamento de Farmacia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, GTO, Mexico.
Nimsi Campos-XolalpaDepartamento de Sistemas Biológicos, Universidad Autónoma Metropolitana, Unidad Xochimilco, Mexico City, Mexico.
Juan Ramón Zapata-MoralesDepartamento de Farmacia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, GTO, Mexico.ORCID 0000-0003-0386-0121
Candy Carranza-AlvarezUnidad Académica Multidisciplinaria de la Zona Huasteca, Universidad Autónoma de San Luis Potosí, Ciudad Valles, SLP, Mexico.
Juan Jose Maldonado-MirandaUnidad Académica Multidisciplinaria de la Zona Huasteca, Universidad Autónoma de San Luis Potosí, Ciudad Valles, SLP, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic. A total of 216 medicinal plants belonging to 77 families have been reported as toxic. Of these plants, 76 had been studied, and 140 plants lacked studies regarding their toxicological effects. The toxicity of 16 plants species has been reported in clinical cases, particularly in children. From these plants, deaths have been reported with the consumption of

Identifiers

PMID29234446
PMCPMC5688365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.