ArticleFrontiers in human neuroscience2017
Blunted Diurnal Cortisol Activity in Healthy Adults with Childhood Adversity.
Article in Frontiers in human neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Acculturation and biological stress markers: A systematic review.Psychoneuroendocrinology · 2021Pooled it
- Glucose as fuel for HPA axis regulation: A narrative review on energy metabolism, stress reactivity, and early life adversity.Comprehensive psychoneuroendocrinology · 2026Review
- Hypothalamic-pituitary-adrenal axis attenuation following child sexual abuse distinguishes posttraumatic stress trajectories from late adolescence to midlife.Psychoneuroendocrinology · 2026Article
- Applying the Research Domain Criteria to Social Determinants of Community Mental Health in Low-Resource Settings: A Contextualized Framework with Insights from the TOPOWA Study.Community mental health journal · 2026Article
- Maternal exposure to trace elements and perfluoroalkyl acids and their associations with alterations of the hypothalamic-pituitary-adrenal axis.Environmental research · 2025Article
- Early life adversity and risk for non-communicable health outcomes: challenges and opportunities for a maturing field.BMC medicine · 2025Review
- Review: Suicide and its relationship to aggression and impulsivity.Cognitive, affective & behavioral neuroscience · 2025Review
- Long-Term Effect of Early-Life Arsenic Exposure on Morning Plasma Cortisol in Adults from Antofagasta, Chile.medRxiv : the preprint server for health sciences · 2025Article
- Childhood trauma cortisol and immune cell glucocorticoid transcript levels are associated with increased risk for suicidality in adolescence.Molecular psychiatry · 2025Article
- Do not exclude your observations: Negative cortisol awakening responses (CAR) may be biologically relevant.Psychoneuroendocrinology · 2025Article
- Lifetime Stressor Severity and Diurnal Cortisol in Older African American Adults: A Comparison of Three Theoretical Models.Developmental psychobiology · 2025Article
- Social and clinical drivers of stress responses in African American breast cancer survivors.Scientific reports · 2024Article
- Sex-specific associations between childhood trauma and adult systemic inflammation in daily life.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- Association among childhood adversity and susceptibility to interference during varying salience: two studies in healthy males.Scientific reports · 2024Article
- Behavioural profiling following acute stress uncovers associations with future stress sensitivity and past childhood abuse.European journal of psychotraumatology · 2024Article
- Genotypic variation in the promoter region of the CRH-248 gene interacts with early rearing experiences to disrupt the development of the HPA axis in infant rhesus macaques (Stress (Amsterdam, Netherlands) · 2024Article
- Article
- Cortisol levels in rural Latina breast cancer survivors participating in a peer-delivered cognitive-behavioral stress management intervention: TheComprehensive psychoneuroendocrinology · 2022Article
- Social Fear in US Infants: The Roles of Hair and Salivary Cortisol.The Yale journal of biology and medicine · 2022Article
- Third trimester cortisol is positively associated with gestational weight gain in pregnant women with class one obesity.International journal of obesity (2005) · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
Abstract
Childhood adversity, such as neglect, or physical, emotional, or sexual abuse, is prevalent in the U.S. and worldwide, and connected to an elevated incidence of disease in adulthood. A pathway in this relationship might be altered hypothalamic-pituitary-adrenal (HPA) axis functioning, as a result of differential hippocampal development in early life. A blunted diurnal cortisol slope is a precursor for many disorders. While studies have focused on HPA reactivity in relation to childhood adversity, there has been markedly less research on basal HPA functioning in those with low-to-moderate adversity. Based on previous research, we hypothesized that adults with low-to-moderate childhood adversity would have altered HPA axis functioning, as evidenced by a blunted diurnal cortisol slope and altered cortisol awakening response (CAR). Healthy adults aged 18-65 (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.