Evidence map›Paper›PMID 29234184›Full record

ArticleIranian journal of medical sciences2017

A Rare Case of Fixed Drug Eruption due to Ondansetron.

Aditi Maitra, Shashwat Bhattacharyya, Sabyasachi Paik, Prerna Pathak, Santanu Kumar Tripathi

Open access · greenAbstract readCase Reports
In one paragraph

Article in Iranian journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aditi MaitraDepartment of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, India.
Shashwat BhattacharyyaDepartment of Ophthalmology, Calcutta National Medical College, Kolkata, India.
Sabyasachi PaikDepartment of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, India.
Prerna PathakDepartment of Dermatology and Venereology, Calcutta School of Tropical Medicine, Kolkata, India.
Santanu Kumar TripathiDepartment of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, India.
Calcutta National Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fixed drug eruption (FDE) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. FDE is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. A 27-year-old woman presented with multiple dark patches over her eyelids, mouth, lips, and shoulders of 1 week's duration. These lesions followed multiple erythematous plaques over the same areas which appeared within 4 hours of the intake of an ondansetron tablet, 12 days previously. The case was diagnosed as post-inflammatory hyperpigmentation following ondansetron-induced FDE. There was an identical episode 1 year earlier due to the intake of the same drug. The causality assessment pointed toward a probable/likely association as per the Naranjo algorithm and the WHO-UMC scale. There have been only a few cases of FDE due to ondansetron in the reported literature.

Indexed as

5HT3 receptor antagonistsFixed drug eruptionHyperpigmentationOndansetron

Identifiers

PMID29234184
PMCPMC5722969
OpenAlexW2581591323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.