Evidence map›Paper›PMID 29234171›Full record

ArticleHeredity2018

The mutational decay of male-male and hermaphrodite-hermaphrodite competitive fitness in the androdioecious nematode C. elegans.

Shu-Dan Yeh, Ayush Shekhar Saxena, Timothy A Crombie, Dorian Feistel, Lindsay M Johnson, Isabel Lam, Jennifer Lam, Sayran Saber, Charles F Baer

Open access · bronzeAbstract read
In one paragraph

Article in Heredity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Variation in mutational (co)variances.G3 (Bethesda, Md.) · 2023
    Article
  4. Phenotypic stasis with genetic divergence.Peer community journal · 2023
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Shu-Dan YehDepartment of Biology, University of Florida, Gainesville, FL, USA.
Ayush Shekhar SaxenaDepartment of Biology, University of Florida, Gainesville, FL, USA.
Timothy A CrombieDepartment of Biology, University of Florida, Gainesville, FL, USA.
Dorian FeistelDepartment of Biology, University of Florida, Gainesville, FL, USA.
Lindsay M JohnsonDepartment of Biology, University of Florida, Gainesville, FL, USA.
Isabel LamDepartment of Biology, University of Florida, Gainesville, FL, USA.
Jennifer LamDepartment of Biology, University of Florida, Gainesville, FL, USA.
Sayran SaberDepartment of Biology, University of Florida, Gainesville, FL, USA.
Charles F BaerDepartment of Biology, University of Florida, Gainesville, FL, USA. cbaer@ufl.edu.
University of Florida · US

Funding

Determination of the distribution of fitness effects of mutations in C. elegansR01GM107227 · NIGMS · UNIVERSITY OF FLORIDA · PI BAER, CHARLES F · 2014 to 2017
$1.1M
Union Biometrica BIOSORTER PRO large-particle flow cytometerS10OD012006 · OD · UNIVERSITY OF FLORIDA · PI BAER, CHARLES F · 2013 to 2013
$600k
NIGMS NIH HHS R01 GM107227NIH HHS S10 OD012006
6 · The paper itself

Abstract

Androdioecious Caenorhabditis have a high frequency of self-compatible hermaphrodites and a low frequency of males. The effects of mutations on male fitness are of interest for two reasons. First, when males are rare, selection on male-specific mutations is less efficient than in hermaphrodites. Second, males may present a larger mutational target than hermaphrodites because of the different ways in which fitness accrues in the two sexes. We report the first estimates of male-specific mutational effects in an androdioecious organism. The rate of male-specific inviable or sterile mutations is ⩽5 × 10

Indexed as

MutationAnimalsCaenorhabditis elegansCompetitive BehaviorFemaleGenetic FitnessHermaphroditic OrganismsMaleModels, GeneticSelection, GeneticSex RatioSexual Behavior, Animal

Identifiers

PMID29234171
PMCPMC5837113
OpenAlexW2767327444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.