ArticleScientific reports2017
Structural reorganization of the early visual cortex following Braille training in sighted adults.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Article
- Article
- Metabolic alterations within the primary visual cortex in blind patients with end-stage glaucoma: a proton magnetic resonance spectroscopy study.Frontiers in cell and developmental biology · 2025Article
- Neural specialization for 'visual' concepts emerges in the absence of vision.bioRxiv : the preprint server for biology · 2024Article
- How learning to read Braille in visual and tactile domains reorganizes the sighted brain.Frontiers in neuroscience · 2024Article
- Gene-agnostic approaches to treating inherited retinal degenerations.Frontiers in cell and developmental biology · 2023Review
- Loss of action-related function and connectivity in the blind extrastriate body area.Frontiers in neuroscience · 2023Article
- Relationship between Tactile Sensation, Motor Activity, and Differential Brain Activity in Young Individuals.Brain sciences · 2022Article
- Neuroplasticity and Crossmodal Connectivity in the Normal, Healthy Brain.Psychology & neuroscience · 2021Article
- Temporal Dynamics of Brain White Matter Plasticity in Sighted Subjects during Tactile Braille Learning: A Longitudinal Diffusion Tensor Imaging Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Tactile to visual number priming in the left intraparietal cortex of sighted Braille readers.Scientific reports · 2020Article
- Neuroplasticity and Braille reading.Acta clinica Croatica · 2020Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Training can induce cross-modal plasticity in the human cortex. A well-known example of this phenomenon is the recruitment of visual areas for tactile and auditory processing. It remains unclear to what extent such plasticity is associated with changes in anatomy. Here we enrolled 29 sighted adults into a nine-month tactile Braille-reading training, and used voxel-based morphometry and diffusion tensor imaging to describe the resulting anatomical changes. In addition, we collected resting-state fMRI data to relate these changes to functional connectivity between visual and somatosensory-motor cortices. Following Braille-training, we observed substantial grey and white matter reorganization in the anterior part of early visual cortex (peripheral visual field). Moreover, relative to its posterior, foveal part, the peripheral representation of early visual cortex had stronger functional connections to somatosensory and motor cortices even before the onset of training. Previous studies show that the early visual cortex can be functionally recruited for tactile discrimination, including recognition of Braille characters. Our results demonstrate that reorganization in this region induced by tactile training can also be anatomical. This change most likely reflects a strengthening of existing connectivity between the peripheral visual cortex and somatosensory cortices, which suggests a putative mechanism for cross-modal recruitment of visual areas.
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