Evidence map›Paper›PMID 29233914›Full record

ArticleG3 (Bethesda, Md.)2018

Had1 Is Required for Cell Wall Integrity and Fungal Virulence in

Won-Hee Jung, Ye-Eun Son, Sang-Hun Oh, Ci Fu, Hye Shin Kim, Jin-Hwan Kwak, Maria E Cardenas, Joseph Heitman, Hee-Soo Park

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Zinc Finger Proteins in the Human Fungal PathogenInternational journal of molecular sciences · 2020
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Won-Hee JungSchool of Food Science and Biotechnology, Institute of Agricultural Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0003-0002-6342
Ye-Eun SonSchool of Food Science and Biotechnology, Institute of Agricultural Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.
Sang-Hun OhSchool of Life Science, Handong Global University, Pohang 37554, Republic of Korea.
Ci FuDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710.
Hye Shin KimSchool of Life Science, Handong Global University, Pohang 37554, Republic of Korea.
Jin-Hwan KwakSchool of Life Science, Handong Global University, Pohang 37554, Republic of Korea.
Maria E CardenasDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710.
Joseph HeitmanDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710.
Hee-Soo ParkSchool of Food Science and Biotechnology, Institute of Agricultural Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea phsoo97@knu.ac.kr.ORCID 0000-0003-4303-9418

Funding

Novel Antifungal Therapeutic ApproachesR01AI050438 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2001 to 2012
$3.3M
Structural Biological Development of Fungal-Specific Calcineurin InhibitorsR01AI112595 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH, SCHUMACHER, MARIA · 2014 to 2017
$2.5M
Activation of rapamycin-sensitive TORC1 by endomembrane amino acid transportersR01CA154499 · NCI · DUKE UNIVERSITY · PI CARDENAS-CORONA, MARIA E · 2011 to 2015
$1.6M
Structural Biological Development of Fungal-Specific Calcineurin InhibitorsR56AI112595 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH, HONG, JIYONG · 2020 to 2020
$669k
NCI NIH HHS R01 CA154499NIAID NIH HHS R01 AI050438NIAID NIH HHS R01 AI112595NIAID NIH HHS R56 AI112595
6 · The paper itself

Abstract

Calcineurin modulates environmental stress survival and virulence of the human fungal pathogen

Indexed as

Adaptation, PhysiologicalAnimalsCell WallCryptococcosisCryptococcus neoformansFemaleFungal ProteinsGene Expression Regulation, FungalHot TemperatureHumansHydrolasesMice, Inbred BALB CMutationVirulenceFungal ProteinsHydrolasescalcineurinCryptococcus neoformansCrz1fungal virulenceHad1

Identifiers

PMID29233914
PMCPMC5919746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.