Evidence map›Paper›PMID 29233906›Full record

Trial reportPhysiological reports2017

Skeletal muscle insulin signaling and whole-body glucose metabolism following acute sleep restriction in healthy males.

Emma L Sweeney, Stewart Jeromson, D Lee Hamilton, Naomi E Brooks, Ian H Walshe

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Sleep habits in the pathogenesis and management of diabesity.Journal of diabetes investigation · 2025
    Review
  8. Article
  9. Gut microbiota in overweight and obesity: crosstalk with adipose tissue.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  10. Article
  11. Nutrient timing and metabolic regulation.The Journal of physiology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Differently Expressed Genes (DEGs) Relevant to Type 2 Diabetes Mellitus Identification and Pathway Analysis via Integrated Bioinformatics Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Emma L SweeneyPhysiology, Exercise and Nutrition Research Group, University of Stirling, Stirling, Scotland, United Kingdom.
Stewart JeromsonPhysiology, Exercise and Nutrition Research Group, University of Stirling, Stirling, Scotland, United Kingdom.
D Lee HamiltonPhysiology, Exercise and Nutrition Research Group, University of Stirling, Stirling, Scotland, United Kingdom.
Naomi E BrooksPhysiology, Exercise and Nutrition Research Group, University of Stirling, Stirling, Scotland, United Kingdom.
Ian H WalshePhysiology, Exercise and Nutrition Research Group, University of Stirling, Stirling, Scotland, United Kingdom.
University of Stirling · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep restriction is associated with impaired glucose metabolism and insulin resistance, however, the underlying mechanisms leading to this impairment are unknown. This study aimed to assess whether the decrease in insulin sensitivity observed after sleep restriction is accompanied by changes in skeletal muscle PKB activity. Ten healthy young males participated in this randomized crossover study which included two conditions separated by a 3-week washout period. Participants underwent two nights of habitual sleep (CON) and two nights of sleep which was restricted to 50% of habitual sleep duration (SR) in the home environment. Whole-body glucose tolerance and insulin sensitivity were assessed by an oral glucose tolerance test after the second night of each condition. Skeletal muscle tissue samples were obtained from the vastus lateralis to determine PKB activity. Findings displayed no effect of trial on plasma glucose concentrations (

Indexed as

AdolescentAdultGlucoseHumansInsulinInsulin ResistanceMaleMuscle, SkeletalProto-Oncogene Proteins c-aktSignal TransductionSleep DeprivationGlucoseInsulinProto-Oncogene Proteins c-aktGlucose tolerancemetabolismperipheral insulin signalingPKB activity

Identifiers

PMID29233906
PMCPMC5727269
OpenAlexW2770379531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.