ArticleBMC oral health2017
Prevalence of Epstein-Barr virus DNA and Porphyromonas gingivalis in Japanese peri-implantitis patients.
Article in BMC oral health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Pooled it
- Efficacy of a bioflavonoid-enriched herbal versus 0.12% and 0.2% chlorhexidine mouthwashes in reducing peri-implant inflammation and subgingival Porphyromonas gingivalis carriage in patients with peri-implantitis.Acta odontologica Scandinavica · 2025Trial
- The oral microbiota in oral squamous cell carcinoma: unravelling mechanisms and clinical potential.Cancer cell international · 2026Review
- Association of Herpes Virus Type 1, Cytomegalo Virus and Epstein-Barr Virus to the Pathogenesis of Peri-Implantitis: A Cross-Sectional Study.Dentistry journal · 2025Article
- The Effect of Xanthohumol and Thymol onCells · 2024Article
- The Impact ofInternational journal of molecular sciences · 2024Article
- Review
- Retrospective analysis ofMolecular and clinical oncology · 2023Article
- The Oral Microbiome as Mediator between Oral Hygiene and Its Impact on Nasopharyngeal Carcinoma.Microorganisms · 2023Article
- Article
- The human oral virome: Shedding light on the dark matter.Periodontology 2000 · 2021Review
- Association of oral Epstein-Barr virus with periodontal health in Japanese adults.Experimental and therapeutic medicine · 2021Article
- Epstein-Barr Virus-Oral Bacterial Link in the Development of Oral Squamous Cell Carcinoma.Pathogens (Basel, Switzerland) · 2020Review
- The Microbiome of Peri-Implantitis: A Systematic Review and Meta-Analysis.Microorganisms · 2020Review
- How Does Epstein-Barr Virus Contribute to Chronic Periodontitis?International journal of molecular sciences · 2020Review
- Herpesvirus-bacteria synergistic interaction in periodontitis.Periodontology 2000 · 2020Review
- A Novel Full-Digital Protocol (SCAN-PLAN-MAKE-DONEInternational journal of environmental research and public health · 2019Article
- Prevalence of herpesviruses in periodontal disease of the North Indian population: A pilot study.Journal of Indian Society of PeriodontologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPeri-implantitis (PI) is an inflammatory reaction associated with functional deterioration of supporting bones around the dental implant. Recent studies suggested Epstein-Barr virus (EBV) is involved in the pathogenesis of periodontitis. We investigated the association between EBV and Porphyromonas gingivalis in Japanese PI patients.
methodsFifteen periodontally healthy individuals, 15 healthy implant patients and 15 PI patients were recruited. Forty five subgingival plaque samples were collected from the deepest probing pocket depth (PPD) site from each patient. Real-time PCR was used to detect EBV DNA and P. gingivalis.
resultsEBV and P. gingivalis were detected in 7 and 3 PPD sites of the healthy controls, in 9 and 4 PPD sites of the healthy implants, and in 13 and 14 PPD sites of the PI patients. P. gingivalis and coexistence of EBV and P. gingivalis were detected significantly higher in the PI patients than healthy controls and healthy implant patients. EBV was detected significantly higher in the PI patients than healthy controls.
conclusionsHigher levels of EBV and P. gingivalis were detected in PPD sites of PI patients. These results suggest that coexistence of EBV and P. gingivalis may serve pathogenic factors cause for PI in Japanese dental patients.
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