Evidence map›Paper›PMID 29233120›Full record

ArticleBMC cancer2017

Prediction of 5-year overall survival in cervical cancer patients treated with radical hysterectomy using computational intelligence methods.

Bogdan Obrzut, Maciej Kusy, Andrzej Semczuk, Marzanna Obrzut, Jacek Kluska

Abstract read
In one paragraph

Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bogdan ObrzutDepartment of Gynaecology and Obstetrics, Faculty of Medicine, University of Rzeszow, Lwowska 60, Rzeszow, 35-301, Poland.
Maciej KusyFaculty of Electrical and Computer Engineering, Rzeszow University of Technology, al. Powstancow Warszawy 12, Rzeszow, 35-959, Poland. mkusy@prz.edu.pl.
Andrzej SemczukIIND Department of Gynecology, Lublin Medical University, al. Raclawickie 1, Lublin, 20-059, Poland.
Marzanna ObrzutFaculty of Medicine, University of Rzeszow, al. Kopisto 2a, Rzeszow, 35-959, Poland.
Jacek KluskaFaculty of Electrical and Computer Engineering, Rzeszow University of Technology, al. Powstancow Warszawy 12, Rzeszow, 35-959, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComputational intelligence methods, including non-linear classification algorithms, can be used in medical research and practice as a decision making tool. This study aimed to evaluate the usefulness of artificial intelligence models for 5-year overall survival prediction in patients with cervical cancer treated by radical hysterectomy.

methodsThe data set was collected from 102 patients with cervical cancer FIGO stage IA2-IIB, that underwent primary surgical treatment. Twenty-three demographic, tumor-related parameters and selected perioperative data of each patient were collected. The simulations involved six computational intelligence methods: the probabilistic neural network (PNN), multilayer perceptron network, gene expression programming classifier, support vector machines algorithm, radial basis function neural network and k-Means algorithm. The prediction ability of the models was determined based on the accuracy, sensitivity, specificity, as well as the area under the receiver operating characteristic curve. The results of the computational intelligence methods were compared with the results of linear regression analysis as a reference model.

resultsThe best results were obtained by the PNN model. This neural network provided very high prediction ability with an accuracy of 0.892 and sensitivity of 0.975. The area under the receiver operating characteristics curve of PNN was also high, 0.818. The outcomes obtained by other classifiers were markedly worse.

conclusionsThe PNN model is an effective tool for predicting 5-year overall survival in cervical cancer patients treated with radical hysterectomy.

Indexed as

Neural Networks, ComputerAdultAgedFemaleFollow-Up StudiesHumansHysterectomyMiddle AgedPostoperative ComplicationsROC CurveSupport Vector MachineSurvival AnalysisUterine Cervical Neoplasms5–year overall survivalCervical cancerComputational intelligence methodsProbabilistic neural network

Identifiers

PMID29233120
PMCPMC5727988

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.