Evidence map›Paper›PMID 29233119›Full record

ArticleBMC gastroenterology2017

Psychological wellbeing and physical activity in children and adolescents with inflammatory bowel disease compared to healthy controls.

Laura Mählmann, Markus Gerber, Raoul I Furlano, Corinne Legeret, Nadeem Kalak, Edith Holsboer-Trachsler, Serge Brand

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02264275 (The Influence of Aerobic Exercise Training on Disease Symptoms, Cardiovascular Fitness, Depression, Sleep and Quality of Life in Children and Adolescents Suffering From Inflammatory Bowel Disease in Switzerland), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02264275 naunknown statusnot on this map

The Influence of Aerobic Exercise Training on Disease Symptoms, Cardiovascular Fitness, Depression, Sleep and Quality of Life in Children and Adolescents Suffering From Inflammatory Bowel Disease in Switzerland

TypeinterventionalSponsorUniversity of BaselRan2014 to 2015Enrolled60ConditionsUlcerative Colitis, Crohn Disease, Depression, SleepArmsAerobic Exercise Training
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  5. Impaired physical fitness in pediatric inflammatory bowel disease.Journal of pediatric gastroenterology and nutrition · 2025
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  15. [Role of NLRP1 and NLRP3 inflammasome signaling pathways in the immune mechanism of inflammatory bowel disease in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Laura MählmannPsychiatric Clinics of the University of Basel, Centre for Affective, Stress and Sleep Disorders, University of Basel, Wilhelm Klein-Strasse 27, Ch-4012, Basel, Switzerland. laura.maehlmann@upkbs.ch.ORCID http://orcid.org/0000-0003-0836-4282
Markus GerberDepartment of Sport, Exercise and Health, Sport Science Section, University of Basel, Basel, Switzerland.
Raoul I FurlanoPediatric Gastroenterology & Nutrition, University Children's Hospital Basel, Basel, Switzerland.
Corinne LegeretPediatric Gastroenterology & Nutrition, University Children's Hospital Basel, Basel, Switzerland.
Nadeem KalakPsychiatric Clinics of the University of Basel, Centre for Affective, Stress and Sleep Disorders, University of Basel, Wilhelm Klein-Strasse 27, Ch-4012, Basel, Switzerland.
Edith Holsboer-TrachslerPsychiatric Clinics of the University of Basel, Centre for Affective, Stress and Sleep Disorders, University of Basel, Wilhelm Klein-Strasse 27, Ch-4012, Basel, Switzerland.
Serge BrandPsychiatric Clinics of the University of Basel, Centre for Affective, Stress and Sleep Disorders, University of Basel, Wilhelm Klein-Strasse 27, Ch-4012, Basel, Switzerland.
University of Basel · CHUniversity Children’s Hospital Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren and adolescents with inflammatory bowel disease (IBD) report impairments in daily activities, social interactions and coping. Findings regarding psychological functioning are inconsistent, while limited information is available on objectively assessed physical activity (PA). The aims of the present study were therefore to compare anthropometric dimensions, blood values, psychological functioning and PA of children and adolescents with IBD with healthy controls.

methodsForty-seven children and adolescents took part in the study. Of these, 23 were diagnosed with IBD (mean age: 13.88 years, 44% females). The IBD group was divided into a medically well adjusted "remission-group" (n = 14; IBD-RE) and a group with an "active state" of disease (n = 8; IBD-AD). Healthy controls (n = 24; HC) were age- and gender-matched. Participants' anthropometric data, blood values and objective PA were assessed. Further, participants completed questionnaires covering socio-demographic data and psychological functioning.

resultsParticipants with IBD-AD showed higher erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) values, haemoglobin, and leukocyte values. IBD-AD had poorer psychological functioning and lower PA (average steps per day) compared to IBD-RE and HC. No mean differences were found between IBD-RE and HC.

conclusionsThe pattern of results suggests that effective medical treatment of IBD in children and adolescents is associated with favorable physiological parameters, psychological dimensions and PA. Psychological counselling of children and adolescents in an active state of IBD seem to be advised in addition to standard treatment schedules.

trial registrationNCT NCT02264275 ; Registered 8 October 2014.

Indexed as

Adaptation, PsychologicalExerciseAdolescentAnthropometryBlood SedimentationChildC-Reactive ProteinFemaleHemoglobinometryHumansInflammatory Bowel DiseasesLeukocytesMaleQuality of LifeSocial SupportSurveys and QuestionnairesC-Reactive ProteinAnthropometric dimensionsBlood valuesHealthy controlsInflammatory bowel diseasesPediatricsPhysical activityPsychological wellbeing

Identifiers

PMID29233119
PMCPMC5727963
OpenAlexW2772037226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.