Observational studyThe Korean journal of internal medicine2019
Factors associated with time to diagnosis from symptom onset in patients with early rheumatoid arthritis.
Observational study in The Korean journal of internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Geroprotective efficacy of Triphalaguggul: a polyherbal formulation against inflammatory disorders through inhibition of pro-inflammatory cytokines as therapeutic biomarkers.Biogerontology · 2026Article
- Risks of autoimmune and inflammatory post-acute COVID-19 conditions: a network cohort study in six European countries, the USA and Korea.BMJ public health · 2026Article
- Sociodemographic and economic barriers to initial specialist care for patients with rheumatoid arthritis: a scoping review.BMC rheumatology · 2025Article
- Expression profiles of miR-101-3p and miR-431-5p as potential diagnostic biomarkers for rheumatoid arthritis.Scientific reports · 2025Article
- Musculoskeletal ultrasonography versus conventional radiography: Correlation with DAS28 and MDHAQ scores in early rheumatoid arthritis.The Journal of international medical research · 2024Article
- Diagnostic delays of periodontitis and associated factors: a cross-sectional study.Clinical oral investigations · 2024Article
- Review
- Association of rheumatoid arthritis with age-related macular degeneration in nationwide longitudinal cohort study.Scientific reports · 2024Article
- Factors affecting the duration of initial medical care seeking among older rural patients diagnosed with rheumatoid arthritis: a retrospective cohort study.BMC rheumatology · 2024Article
- Epidemiology and Risk Factors for Rheumatoid Arthritis Development.Mediterranean journal of rheumatology · 2023Review
- Factors Leading to Diagnostic and Therapeutic Delay of Rheumatoid Arthritis and Their Impact on Disease Outcome.Cureus · 2023Article
- Socioeconomic Status and Medication Use in Rheumatoid Arthritis: A Scoping Review.Arthritis care & research · 2023Article
- Factors Associated With Quality Care Among Adults With Rheumatoid Arthritis.JAMA network open · 2022Article
- Frequency of Interstitial Lung Disease in Rheumatoid Arthritis Patients: A Hospital-Based Study.Cureus · 2022Article
- The relationship between patients' income and education and their access to pharmacological chronic pain management: A scoping review.Canadian journal of pain = Revue canadienne de la douleur · 2022Article
- Anti-arthritic activity ofIranian journal of basic medical sciences · 2021Article
- Long Noncoding RNAs and Circular RNAs in Autoimmune Diseases.Biomolecules · 2020Review
- Quantitative Predictive Modelling Approaches to Understanding Rheumatoid Arthritis: A Brief Review.Cells · 2019Review
- Analysis of Socioeconomic Status in the Patients with Rheumatoid Arthritis.International journal of environmental research and public health · 2018Article
- Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies.Bone research · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
BACKGROUND/
aimsTo identify the factors associated with time to diagnosis after symptom onset in patients with early rheumatoid arthritis (RA).
methodsEarly RA patients with ≤ 1 year of disease duration in the KORean Observational study Network for Arthritis (KORONA) database were included in this analysis. Patients were further divided into two groups according to the time to diagnosis from symptom onset: the early diagnosis group (time to diagnosis ≤ 1 year) and the late diagnosis group (time to diagnosis > 1 year). Using the multivariable regression model, we identified factors associated with early diagnosis.
resultsAmong 714 early RA patients, 401 patients (56.2%) and 313 patients (43.8%) were included in the early diagnosis and late diagnosis groups, respectively. The mean disease duration was 0.47 years in the early diagnosis group and 0.45 years in the late diagnosis group. In multivariable model analysis, greater age at onset (odds ratio [OR], 1.03; 95% confidence interval [CI], 1.02 to 1.05), high school education or higher (OR, 1.68; 95% CI, 1.14 to 2.47), higher income (OR, 1.48; 95% CI, 1.05 to 2.08), and initial small joint involvement (OR, 1.42; 95% CI, 1.02 to 1.98) were factors associated with early diagnosis. At diagnosis, disease activity scores using 28 joints on diagnosis (3.81 ± 1.44 vs. 3.82 ± 1.42, p = 0.92) and functional disability (0.65 ± 0.61 vs. 0.57 ± 0.62, p = 0.07) did not different between the two groups. However, hand joint erosion on X-ray (37.8% vs. 25.6%, p < 0.01) was more common in the late diagnosis group than the early diagnosis group.
conclusionOlder onset age, higher educational level and income, and initial small joint involvement were positive factors for early diagnosis of RA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.