Evidence map›Paper›PMID 29232903›Full record

ReviewMedicines (Basel, Switzerland)2017

Pediatric Thermal Burns and Treatment: A Review of Progress and Future Prospects.

Elton Mathias, Madhu Srinivas Murthy

Open access · goldAbstract readReview
In one paragraph

Review in Medicines (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. 3‴-Plants (Basel, Switzerland) · 2023
    Article
  6. Parents' lived experience of living with and caring for their burn-injured child in a home setting.International journal of qualitative studies on health and well-being · 2023
    Article
  7. Pediatric Craniofacial and Neck Burns.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  8. Article
  9. Pain Management in Pediatric Burns: A Review of the Science behind It.Global health, epidemiology and genomics · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. PD-L1Science advances · 2021
    Article
  15. Article
  16. Topical Wound Healing Activity of Myricetin Isolated fromMolecules (Basel, Switzerland) · 2020
    Article
  17. Article
  18. Article
  19. The Course of Scar Formation and Predictors of Scar Quality in 490 Paediatric Burn Patients During the First Year Post-Burn.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Elton MathiasDepartment of Clinical Research, Mallinckrodt Pharmaceuticals, Bedminster, NJ 07921, USA. elton.mathias@mallinckrodt.com.
Madhu Srinivas MurthyCentre for Applied Genetics, Bangalore University, Bangalore 560056, India. madhu.srinivas06@gmail.com.ORCID 0000-0002-3881-3440
Bangalore University · INMallinckrodt (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burn injuries are a devastating critical care problem. In children, burns continue to be a major epidemiologic problem around the globe resulting in significant morbidity and death. Apparently, treating these burn injuries in children and adults remains similar, but there are significant physiological and psychological differences. The dermal layer of the skin is generally thinner in neonates, infants, and children than in adults. Enhanced evaporative loss and need for isotonic fluids increases the risk of hypothermia in the pediatric population. The pain management of the children with major burns challenges the skills of the personnel of every unit. Managing these wounds requires intensive therapeutic treatment for multi-organ dysfunction, and surgical treatment to prevent sepsis and other complications that further delay wound closure. Alternatives to the practice of donor site harvest and autografting for the treatment of severe burns and other complex skin defects are urgently needed for both adult and pediatric populations. This review article focuses on thermal burn pathophysiology and pain management and provides an overview of currently approved products used for the treatment of pediatric burn wounds. A new promising approach has been presented as a first-line therapy in the treatment of burns to reduce surgical autografting in pediatric patients.

Indexed as

autograftbiological skin substituteburnspediatricthermaltreatment

Identifiers

PMID29232903
PMCPMC5750615
OpenAlexW2774212996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.