ArticleInternational journal of molecular sciences2017
Synthesis and Characterization of Nanofunctionalized Gelatin Methacrylate Hydrogels.
Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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The trial behind it
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Who cites it
43 citing papers in PubMed.
- Modern Drug Delivery Platforms Based on Photocrosslinkable Hydrogels (PCHs) in Dentistry: From Material Characteristics to Clinical Applications-A Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Physicochemical, Sensorial and Calcium Bioavailability of Jelly Prepared Using Fish Gelatin in Combination with Furcellaran and Calcium L-Threonate.Gels (Basel, Switzerland) · 2025Article
- Mesenchymal stem cell-laden double-network hydrogel nerve guidance conduits for peripheral nerve injury repair.Bioactive materials · 2025Article
- The construction of the gelatin methacrylate microneedle -encapsulated newcastle disease virus and its antitumor effect in hepatocellular carcinoma.Journal of biological engineering · 2025Article
- Thermally Cured Gelatin-Methacryloyl Hydrogels Form Mechanically Modulating Platforms for Cell Studies.Biomacromolecules · 2025Article
- Formation and Characterization of Xylitol-Modified Glycidyl Methacrylate-Molecules (Basel, Switzerland) · 2025Article
- Transplantation of human embryonic stem cell-derived retinal pigment epithelial cells via injectable microfluidic-templated microgels for retinal regeneration.Materials today. Bio · 2025Article
- Integration of co-culture conditions and 3D gelatin methacryloyl hydrogels to improve human-induced pluripotent stem cells-derived cardiomyocytes maturation.Frontiers in bioengineering and biotechnology · 2025Article
- One-pot synthesis of polysaccharide/gelatin amorphous hydrogels impregnated with a bioflavonoid derived from Elaeis guineensis leaf: wound healing and drug release properties.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024Article
- Enhancing Mucoadhesive Properties of Gelatin through Chemical Modification with Unsaturated Anhydrides.Biomacromolecules · 2024Article
- Cryogenic 3D Printing of GelMA/Graphene Bioinks: Improved Mechanical Strength and Structural Properties for Tissue Engineering.International journal of nanomedicine · 2024Article
- Photo-crosslinked gelatin methacryloyl hydrogel strengthened with calcium phosphate-based nanoparticles for early healing of rabbit calvarial defects.Journal of periodontal & implant science · 2023Article
- Hydrogel-Impregnated Self-Oxygenating Electrospun Scaffolds for Bone Tissue Engineering.Bioengineering (Basel, Switzerland) · 2023Article
- Injectable, stretchable, toughened, bioadhesive composite hydrogel for bladder injury repair.RSC advances · 2023Article
- MSCs-laden silk Fibroin/GelMA hydrogels with incorporation of platelet-rich plasma for chondrogenic construct.Heliyon · 2023Article
- Fabrication and optimization of 3D printed gelatin methacryloyl microneedle arrays based on vat photopolymerization.Frontiers in bioengineering and biotechnology · 2023Article
- Inorganic/Biopolymers Hybrid Hydrogels Dual Cross-Linked for Bone Tissue Regeneration.Gels (Basel, Switzerland) · 2022Article
- 3D printed biomimetic epithelium/stroma bilayer hydrogel implant for corneal regeneration.Bioactive materials · 2022Article
- Article
- Photocrosslinkable methacrylated gelatin hydrogel as a cell-friendly injectable delivery system for chlorhexidine in regenerative endodontics.Dental materials : official publication of the Academy of Dental Materials · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Given the importance of the extracellular medium during tissue formation, it was wise to develop an artificial structure that mimics the extracellular matrix while having improved physico-chemical properties. That is why the choice was focused on gelatin methacryloyl (GelMA), an inexpensive biocompatible hydrogel. Physicochemical and mechanical properties were improved by the incorporation of nanoparticles developed from two innovative fabrication processes: High shear fluid and low frequencies/high frequencies ultrasounds. Both rapeseed nanoliposomes and nanodroplets were successfully incorporated in the GelMA networks during the photo polymerization process. The impact on polymer microstructure was investigated by Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and enzymatic degradation investigations. Mechanical stability and viscoelastic tests were conducted to demonstrate the beneficial effect of the functionalization on GelMA hydrogels. Adding nanoparticles to GelMA improved the surface properties (porosity), tuned swelling, and degradability properties. In addition, we observed that nanoemulsion didn't change significantly the mechanical properties to shear and compression solicitations, whereas nanoliposome addition decreased Young's modulus under compression solicitations. Thus, these ways of functionalization allow controlling the design of the material by choosing the type of nanoparticle (nanoliposome or nanoemulsion) in function of the application.
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Registered trials
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