Evidence map›Paper›PMID 29231925›Full record

ArticleScientific data2017

Expression profiling of the retina of pde6c, a zebrafish model of retinal degeneration.

Liyun Zhang, Xinlian Zhang, Gaonan Zhang, Chi Pui Pang, Yuk Fai Leung, Mingzhi Zhang, Wenxuan Zhong

Abstract readDataset
In one paragraph

Article in Scientific data, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  7. Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
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  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liyun ZhangDepartment of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN 47907, USA.
Xinlian ZhangDepartment of Statistics, University of Georgia, 101 Cedar St, Athens, GA 30602, USA.
Gaonan ZhangDepartment of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN 47907, USA.
Chi Pui PangDepartment of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong.
Yuk Fai LeungDepartment of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN 47907, USA.
Mingzhi ZhangJoint Shantou International Eye Center, Shantou University & the Chinese University of Hong Kong, Shantou 515041, China.
Wenxuan ZhongDepartment of Statistics, University of Georgia, 101 Cedar St, Athens, GA 30602, USA.

Funding

Novel statistical tools for cell line specific epigenetic analysisR01GM113242 · NIGMS · UNIVERSITY OF GEORGIA · PI ZHONG, WENXUAN · 2014 to 2017
$1.4M
Deciphering the Regulatory Role of Small RNAs on Alternative Splicing R01GM122080 · NIGMS · UNIVERSITY OF GEORGIA · PI MA, PING · 2016 to 2019
$1.3M
NIGMS NIH HHS R01 GM113242NIGMS NIH HHS R01 GM122080
6 · The paper itself

Abstract

Retinal degeneration often affects the whole retina even though the disease-causing gene is specifically expressed in the light-sensitive photoreceptors. The molecular basis of the retinal defect can potentially be determined by gene-expression profiling of the whole retina. In this study, we measured the gene-expression profile of retinas microdissected from a zebrafish pde6c

Indexed as

AnimalsCyclic Nucleotide Phosphodiesterases, Type 6Microarray AnalysisRetinaRetinal DegenerationTranscriptomeZebrafishZebrafish ProteinsCyclic Nucleotide Phosphodiesterases, Type 6Pde6c protein, zebrafishZebrafish Proteins

Identifiers

PMID29231925
PMCPMC5726315

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.