Evidence map›Paper›PMID 29231859›Full record

ArticleMolecules (Basel, Switzerland)2017

Rational Engineering of a Flavoprotein Oxidase for Improved Direct Oxidation of Alcohols to Carboxylic Acids.

Mathias Pickl, Christoph K Winkler, Silvia M Glueck, Marco W Fraaije, Kurt Faber

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 276 citations in OpenAlex.

  1. Review
  2. Article
  3. Biocatalytic Enantioselective Oxidation ofAdvanced synthesis & catalysis · 2019
    Article
  4. Special Issue: Flavoenzymes.Molecules (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mathias PicklDepartment of Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria. Mathias.Pickl@edu.uni-graz.at.
Christoph K WinklerAustrian Centre of Industrial Biotechnology, ACIB GmbH c/o Department of Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria. winkler_christoph@hotmail.com.ORCID 0000-0003-3068-9817
Silvia M GlueckAustrian Centre of Industrial Biotechnology, ACIB GmbH c/o Department of Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria. Si.Glueck@uni-graz.at.
Marco W FraaijeMolecular Enzymology Group, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands. m.w.fraaije@rug.nl.
Kurt FaberDepartment of Chemistry, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria. kurt.faber@uni-graz.at.
University of Graz · ATUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oxidation of alcohols to the corresponding carbonyl or carboxyl compounds represents a convenient strategy for the selective introduction of electrophilic carbon centres into carbohydrate-based starting materials. The O₂-dependent oxidation of

Indexed as

Alcohol OxidoreductasesAlcoholsAldehydesCarboxylic AcidsCatalysisCatalytic DomainEscherichia coliFlavinsFlavoproteinsFuraldehydeHydrogen BondingKineticsOxidation-ReductionProtein Conformation5-hydroxymethylfurfuralalcohol oxidaseAlcohol OxidoreductasesAlcoholsAldehydesCarboxylic AcidsFlavinsFlavoproteinsFuraldehydealcohol oxidationaldehyde oxidationbiocatalysisflavoprotein oxidaseprotein design

Identifiers

PMID29231859
PMCPMC6149797
OpenAlexW2773553108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.