ArticleThe American journal of gastroenterology2018
Lesions of All Types Exist in Colon Polyps of All Sizes.
Article in The American journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- The absolute number of small and diminutive adenomas with high-grade dysplasia is substantially higher compared with large adenomas: a retrospective pooled study.Frontiers in oncology · 2024Pooled it
- Pooled it
- Prevalence and Clinical Features of Sessile Serrated Polyps: A Systematic Review.Gastroenterology · 2020Pooled it
- Effectiveness and safety of the different endoscopic resection methods for 10- to 20-mm nonpedunculated colorectal polyps: A systematic review and pooled analysis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationPooled it
- Risk Prediction for Delayed Bleeding After Endoscopic Submucosal Dissection in Colorectal Precancerous Lesions Using Artificial Intelligence: Retrospective Clinical Trial.Diseases of the colon and rectum · 2026Article
- Endoscopic characterization and development of a prediction model for colorectal adenomatous polyps.World journal of gastrointestinal surgery · 2026Article
- Colorectal Polyp Size Measurement Faces Infinite Possibilities: Artificial Intelligence Is the Key.Digestion · 2026Review
- A novel cloud-based artificial intelligence for real-time detection of colorectal neoplasia - a randomized controlled trial (EAGLE).NPJ digital medicine · 2025Article
- Updates in the endoscopic management of colorectal polyps.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Review
- Combating Post-colonoscopy Colorectal Cancer: Insight from the Trials and Cohort Studies.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- New chapter in precision medicine: strategies for endoscopic resection of 10-20 mm non-pedunculated colorectal polyps.Therapeutic advances in gastroenterology · 2025Review
- Endoscopic characteristics to differentiate SSLs and microvesicular hyperplastic polyps from goblet cell-rich hyperplastic polyps.Endoscopy international open · 2024Article
- Usefulness of magnifying endoscopy for diagnosis of sessile serrated lesion with dysplasia or carcinoma: Large retrospective study.Endoscopy international open · 2024Article
- Multi-step validation of a deep learning-based system with visual explanations for optical diagnosis of polyps with advanced features.iScience · 2024Article
- Epidemiology and early screening strategies for colorectal cancer in China.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023Article
- Artificial intelligence-based polyp size measurement in gastrointestinal endoscopy using the auxiliary waterjet as a reference.Endoscopy · 2023Article
- Increased Colorectal Neoplasia Risk in Patients with Inflammatory Bowel Disease and Serrated Polyps with Dysplasia.Digestive diseases and sciences · 2022Article
- Artificial intelligence-assisted colonoscopy: a narrative review of current data and clinical applications.Singapore medical journal · 2022Review
- Colonoscopic image synthesis with generative adversarial network for enhanced detection of sessile serrated lesions using convolutional neural network.Scientific reports · 2022Article
- Safety of cold snare polypectomy with periprocedural antithrombotic agents for colorectal polyps: a systematic review and meta-analysis.Therapeutic advances in gastroenterology · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAlthough large polyps are known to harbor more advanced neoplasia than small polyps, the extent of the relationship between size and type is not fully known. The study aim was to establish benchmarks for the prevalence of different histologic polyp types among varying size categories.
methodsThe Miraca Life Sciences Database is an electronic repository of histopathologic patient records from private practices throughout the United States. We extracted the records of 483,998 unique patients who underwent colonoscopy with polypectomy between January 2008 and December 2014. A total of 550,811 polyps were stratified by their endoscopic size measurement. Polyps of each size were further stratified as hyperplastic polyp (HP), tubular adenoma (TA), tubulovillous adenoma (TVA), sessile serrated adenoma/polyp, and adenocarcinoma.
resultsOf all 550,811 polyps, 447,343 (81%) were 1-9 mm in size, and 103,517 (19%) were 10 mm or larger. A fraction of 18,591/550,811 polyps (3.4%) harbored histologic features of advanced adenoma, such as TVA, high-grade dysplasia, or cancer. Of these, 4,725/18,591 (25%) occurred in polyps 1-9 mm and 13,868/18,591 (75%) occurred in polyps 10 mm or larger. The fractions of advanced adenoma were 0.6% (0.5-0.6%) in 1-5 mm polyps and 2.1% (2.0-2.2%) in 6-9 mm polyps, as compared to 13.4% (13.2-13.6%) in polyps 10 mm or larger. The frequency of HP significantly decreased with increasing polyp size, whereas the frequency of TA remained largely unaffected by polyp size.
conclusionsWhile advanced histopathology was found more frequently in colorectal polyps of larger than smaller size, one quarter of all advanced histopathology existed in polyps of <10 mm.
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Registered trials
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