Evidence map›Paper›PMID 29231170›Full record

ArticleeLife2017

Phenotypic diversity and temporal variability in a bacterial signaling network revealed by single-cell FRET.

Johannes M Keegstra, Keita Kamino, François Anquez, Milena D Lazova, Thierry Emonet, Thomas S Shimizu

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
  2. Growth-dependent sensory bet-hedging enhances collective navigation.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Nature physics · 2026
    Article
  7. Article
  8. ChemotaxingArXiv · 2025
    Article
  9. ChemotaxingbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Review
  12. Nongenetic adaptation by collective migration.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Article
  15. Adaptation of a Commercial Qualitative BAXFoods (Basel, Switzerland) · 2023
    Article
  16. Article
  17. A nonequilibrium allosteric model for receptor-kinase complexes: The role of energy dissipation in chemotaxis signaling.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Optimal inference of molecular interaction dynamics in FRET microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johannes M KeegstraAMOLF Institute, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-8877-4881
Keita KaminoAMOLF Institute, Amsterdam, The Netherlands.
François AnquezAMOLF Institute, Amsterdam, The Netherlands.
Milena D LazovaAMOLF Institute, Amsterdam, The Netherlands.
Thierry EmonetDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.ORCID http://orcid.org/0000-0002-6746-6564
Thomas S ShimizuAMOLF Institute, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-0040-7380

Funding

The contribution of phenotypic variability to chemotactic performanceR01GM106189 · NIGMS · YALE UNIVERSITY · PI EMONET, THIERRY · 2013 to 2022
$2.6M
Nederlandse Organisatie voor Wetenschappelijk Onderzoek NWO Vidi 680-47-515NIGMS NIH HHS R01 GM106189NIH HHS R01GM106189Paul G. Allen Family Foundation 11562Stichting voor Fundamenteel Onderzoek der Materie FOM Projectruimte 11PR2958
6 · The paper itself

Abstract

We present

Indexed as

Biological Variation, PopulationChemotaxisSignal TransductionEscherichia coliFluorescence Resonance Energy TransferPhosphorylationProtein KinasesProtein Processing, Post-TranslationalReceptors, Cell SurfaceSingle-Cell AnalysisProtein KinasesReceptors, Cell Surfaceallosterychemotaxiscomputational biologyE. colinoisenon-genetic individualitysignal transductionsystems biologytwo-state switching

Identifiers

PMID29231170
PMCPMC5809149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.