Evidence map›Paper›PMID 29231037›Full record

ArticleChronic illness2019

Energy envelope maintenance among patients with myalgic encephalomyelitis and chronic fatigue syndrome: Implications of limited energy reserves.

Kelly O'connor, Madison Sunnquist, Laura Nicholson, Leonard A Jason, Julia L Newton, Elin B Strand

Abstract readMulticenter Study
In one paragraph

Article in Chronic illness, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelly O'connor1 Center for Community Research, DePaul University, Chicago, IL, USA.
Madison Sunnquist1 Center for Community Research, DePaul University, Chicago, IL, USA.
Laura Nicholson1 Center for Community Research, DePaul University, Chicago, IL, USA.
Leonard A Jason1 Center for Community Research, DePaul University, Chicago, IL, USA.
Julia L Newton2 Newcastle University, Tyne and Wear, UK.
Elin B Strand3 Oslo University Hospital, Oslo, Norway.

Funding

Pediatric CFS in a Community-Based SampleR01HD072208 · NICHD · DE PAUL UNIVERSITY · PI JASON, LEONARD A · 2013 to 2017
$2.0M
NICHD NIH HHS R01 HD072208
6 · The paper itself

Abstract

objectiveThe Energy Envelope Theory of myalgic encephalomyelitis and chronic fatigue syndrome postulates that individuals with myalgic encephalomyelitis and chronic fatigue syndrome may experience some increase in functioning if their level of exertion consistently remains within the limits of their available energy. Findings of several studies support this theory; however, the current study is the first to explore how an individual's initial level of available energy may influence the relation between energy envelope maintenance and level of functioning.

methodThe functioning, activity, and symptomatology of six groups of individuals with myalgic encephalomyelitis and chronic fatigue syndrome were compared. Groups were created based upon level of available energy (higher or lower) and energy envelope adherence (underextended, within, overextended).

resultsResults indicate that, as expected, individuals with myalgic encephalomyelitis and chronic fatigue syndrome who had higher available energy also had better functioning than individuals with lower available energy; however, this relation was less pronounced for individuals who were overexerting themselves. DISCUSSION: These results are consistent with the Energy Envelope Theory, and they suggest that overexertion was particularly impactful for individuals with higher levels of available energy.

Indexed as

AdultCross-Sectional StudiesEnergy MetabolismExerciseFatigue Syndrome, ChronicFemaleHumansMaleMiddle AgedPhysical ExertionQuality of LifeSurveys and Questionnaireschronic fatigue syndromeenergyenergy envelopeMyalgic encephalomyelitispacing

Identifiers

PMID29231037
PMCPMC5750135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.