Evidence map›Paper›PMID 29230836›Full record

ArticleStatistics in medicine2018

Dynamic prediction in functional concurrent regression with an application to child growth.

Andrew Leroux, Luo Xiao, Ciprian Crainiceanu, William Checkley

Abstract read
In one paragraph

Article in Statistics in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Joint Registration and Conformal Prediction for Partially Observed Functional Data.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2026
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  3. Article
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  11. Impact of the COVID-19 induced lockdown measures onAtmospheric environment (Oxford, England : 1994) · 2021
    Article
  12. Article
  13. Novel metrics for growth model selection.Emerging themes in epidemiology · 2018
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew LerouxDepartment of Biostatistics, Johns Hopkins University, Baltimore, MD 21205, USA.
Luo XiaoDepartment of Statistics, North Carolina State University, Raleigh, NC 27606, USA.ORCID 0000-0001-8707-0914
Ciprian CrainiceanuDepartment of Biostatistics, Johns Hopkins University, Baltimore, MD 21205, USA.
William CheckleySchool of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.

Funding

EPIDEMIOLOGY AND BIOSTATISTICS OF AGINGT32AG000247 · NIA · JOHNS HOPKINS UNIVERSITY · PI Karen J. Bandeen-Roche · 1996 to 2026
$13.2M
Statistical Methods for Multilevel Multivariate Functional StudiesR01NS060910 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Ciprian M Crainiceanu · 2009 to 2026
$8.3M
Statistical methods for analyzing objectively measured physical activity dataR01HL130483 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Chongzhi Di · 2016 to 2026
$4.4M
Statistical methods for biosignals with varying domainsR01HL123407 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CRAINICEANU, CIPRIAN M · 2014 to 2017
$1.6M
NHLBI NIH HHS R01 HL123407NHLBI NIH HHS R01 HL130483NIA NIH HHS T32 AG000247NINDS NIH HHS R01 NS060910
6 · The paper itself

Abstract

In many studies, it is of interest to predict the future trajectory of subjects based on their historical data, referred to as dynamic prediction. Mixed effects models have traditionally been used for dynamic prediction. However, the commonly used random intercept and slope model is often not sufficiently flexible for modeling subject-specific trajectories. In addition, there may be useful exposures/predictors of interest that are measured concurrently with the outcome, complicating dynamic prediction. To address these problems, we propose a dynamic functional concurrent regression model to handle the case where both the functional response and the functional predictors are irregularly measured. Currently, such a model cannot be fit by existing software. We apply the model to dynamically predict children's length conditional on prior length, weight, and baseline covariates. Inference on model parameters and subject-specific trajectories is conducted using the mixed effects representation of the proposed model. An extensive simulation study shows that the dynamic functional regression model provides more accurate estimation and inference than existing methods. Methods are supported by fast, flexible, open source software that uses heavily tested smoothing techniques.

Indexed as

Regression AnalysisAnthropometryBody HeightBody WeightChild DevelopmentChild, PreschoolComputer SimulationData Interpretation, StatisticalFemaleForecastingGrowthGrowth ChartsHumansInfantInfant, NewbornMalecovariance functionfacefPCAlongitudinal datamixed effectspenalized splinessparse functional data

Identifiers

PMID29230836
PMCPMC5847461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.