ArticleEJNMMI physics2017
The effect of high count rates on cardiac perfusion quantification in a simultaneous PET-MR system using a cardiac perfusion phantom.
Article in EJNMMI physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Quantitative imaging: systematic review of perfusion/flow phantoms.European radiology experimental · 2020Pooled it
- Impact of improved attenuation correction on 18F-FDG PET/MR hybrid imaging of the heart.PloS one · 2019Trial
- Quantitative myocardial perfusion imaging across PET, SPECT, CMR, and CT.Frontiers in radiology · 2026Review
- A retrospective evaluation of Bayesian-penalized likelihood reconstruction for [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Assessment of a digital and an analog PET/CT system for accurate myocardial perfusion imaging with a flow phantom.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Assessment of left and right ventricular functional parameters using dynamic dual-tracer [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Improved PET/MRI accuracy by use of static transmission source in empirically derived hardware attenuation correction.EJNMMI physics · 2021Article
- Simulation study of a coincidence detection system for non-invasive determination of arterial blood time-activity curve measurements.EJNMMI physics · 2020Article
- SimultaneousEuropean journal of hybrid imaging · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPET-MRI is under investigation as a new strategy for quantitative myocardial perfusion imaging. Consideration is required as to the maximum scanner count rate in order to limit dead-time losses resulting from administered activity in the scanner field of view during the first pass of the radiotracer.
resultsWe performed a decaying-source experiment to investigate the high count-rate performance of a PET-MR system (Siemens mMR) over the expected range of activities during a clinical study. We also performed imaging of a cardiac perfusion phantom, which provides an experimental simulation of clinical transit of a simultaneous radiotracer (phantom injected activities range 252 to 997 MBq) and gadolinium-based contrast agent (GBCA). Time-activity and time-intensity curves of the aorta and myocardium compartments from PET and MR images were determined, and quantification of perfusion was then performed using a standard cardiac kinetic model. The decaying-source experiment showed a maximum noise equivalent count rate (NECR
conclusionsCare should be taken to avoid high count-rate losses in simultaneous PET-MRI studies. Based on our results in phantoms, bias in reconstructed images should be avoided by adhering to a singles rate lower than 64.9 Mcps on the mMR system. Quantification of perfusion values using singles rates higher than 64.9 Mcps on this system may be compromised and should be avoided.
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