Evidence map›Paper›PMID 29230573›Full record

Observational studyHeart and vessels2018

Incidence of perioperative stroke in clampless aortic anastomosis during off-pump coronary artery bypass grafting.

Francesco Formica, Giuseppe Tata, Gurmeet Singh, Serena Mariani, Stefano D'Alessandro, Luigi Amerigo Messina, Fabio Sangalli, Giovanni Paolini

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Heart and vessels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Sequential left internal mammary artery grafting in combination with the aortic no-touch technique.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Francesco FormicaDepartment of Medicine and Surgery, Cardiac Surgery Clinic, San Gerardo Hospital, University of Milano-Bicocca, Via G.B. Pergolesi 33, 20052, Monza, MB, Italy. francesco_formica@fastwebnet.it.
Giuseppe TataCardiac Surgery Unit, Niguarda Hospital, Milano, Italy.
Gurmeet SinghDepartment of Critical Care Medicine and Division of Cardiac Surgery, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.
Serena MarianiCardiac Surgery Unit, Twente Thorax Center, Enschede, The Netherlands.
Stefano D'AlessandroDepartment of Medicine and Surgery, Cardiac Surgery Clinic, San Gerardo Hospital, University of Milano-Bicocca, Via G.B. Pergolesi 33, 20052, Monza, MB, Italy.
Luigi Amerigo MessinaStatistics and Quality Health Service, San Gerardo Hospital, Monza, Italy.
Fabio SangalliDepartment of Anaesthesia and Intensive Care Medicine, San Gerardo Hospital, Monza, Italy.
Giovanni PaoliniDepartment of Medicine and Surgery, Cardiac Surgery Clinic, San Gerardo Hospital, University of Milano-Bicocca, Via G.B. Pergolesi 33, 20052, Monza, MB, Italy.
University of Milano-Bicocca · ITAzienda Ospedaliera San Gerardo · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITUniversity of Alberta · CA

Funding

Università degli Studi di Milano-Bicocca 2010-ATE-0369
6 · The paper itself

Abstract

This study aimed to assess if clampless off-pump coronary artery bypass grafting (OPCAB) decreases the incidence of perioperative stroke (POS) rate and in-hospital mortality. The secondary aim was to evaluate 12-year rates of overall mortality. Between January 2003 to December 2015, data of 645 consecutive patients undergoing isolated CABG were retrospectively collected. 363 underwent aortic no-touch OPCAB (No-touch group) and 282 underwent OPCAB with the Heartstring device (HS group). In-hospital mortality and perioperative stroke rate as primary endpoint, as well as long-term follow-up outcome were analysed. In-hospital mortality was lower into No-touch group compared with HS group but without significant statistical difference (1.7 vs. 3.2%, p = 0.19, respectively); the rate of postoperative stroke was higher in No-touch group compared with HS group, although this difference did not reach statistically significance. Delirium was reported with higher presentation rate in HS group (3.9 vs. 0.8%, p = 0.01). Blood transfusions rate was higher in HS subjects (23.4 vs. 16.1%, p = 0.01). Intubation time, ICU, and hospital length of stay were increased in the HS group (p = 0.008, p = 0.001 and p = 0.003, respectively). Over a 12-year follow-up period, survival probabilities at 1, 5, and 10 years were 93.6 ± 1.3 vs. 93.2 ± 1.5, 80.4 ± 2.6 vs. 80.3 ± 2.2, and 57.9 ± 5 vs. 58.4 ± 3.8% in the No-touch and HS group, respectively (p = 0.97). In this retrospective study, clampless off-pump CABG lowers perioperative stroke rate whose incidence is, however, not inferior compared with No-touch technique, and no statistically significance was detected. Delirium has a higher presentation rate in clampless off-pump CABG.

Indexed as

AgedAged, 80 and overAnastomosis, SurgicalAorta, ThoracicCoronary Artery Bypass, Off-PumpCoronary VesselsFemaleHospital MortalityHumansIncidenceItalyMalePostoperative ComplicationsRetrospective StudiesRisk FactorsStrokeCABGClampless anastomosisOff-pump surgeryStroke

Identifiers

PMID29230573
OpenAlexW2775212809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.