SynthesisClinical oral investigations2018
Influence of different types of light on the response of the pulp tissue in dental bleaching: a systematic review.
Synthesis in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Do Laser and Light Activation Improve In-Office Dental Bleaching Outcomes? An Umbrella Review of Efficacy, Tooth Sensitivity, and Biological Safety.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Pooled it
- Effects of different bleaching methods on the color stability, microhardness, and surface roughness of single-shade composites.BMC oral health · 2025Article
- Effects of different energy levels of Er: YAG laser-assisted bleaching on teeth bleaching efficacy and immediate resin bonding: a study on safety and clinical applicability.Lasers in medical science · 2025Article
- Can different agents reduce the damage caused by bleaching gel to pulp tissue? A systematic review of basic research.Restorative dentistry & endodontics · 2023Article
- Evaluation of dentinal tubule occlusion and pulp tissue response after using 980-nm diode laser for dentin hypersensitivity treatment.Clinical oral investigations · 2023Article
- The Role of Cellular Metabolism in Maintaining the Function of the Dentine-Pulp Complex: A Narrative Review.Metabolites · 2023Review
- Clinical comparison of diode laser- and LED-activated tooth bleaching: 9-month follow-up.Lasers in medical science · 2022Article
- Characterization and effectiveness of a violet LED light for in-office whitening.Clinical oral investigations · 2022Article
- Photobiomodulation reduces inflammation but does not influence the hypoxia-inducible factor-1α in pulp tissue of rats after bleaching.Journal of applied oral science : revista FOB · 2022Article
- Efficiency of Teeth Bleaching after Regenerative Endodontic Treatment: A Systematic Review.Journal of clinical medicine · 2021Review
- Influence of low-level laser therapy on inflammation, collagen fiber maturation, and tertiary dentin deposition in the pulp of bleached teeth.Clinical oral investigations · 2020Article
- Bleaching gel mixed with MI Paste Plus reduces penetration of HClinical oral investigations · 2020Article
- Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats.Journal of applied oral science : revista FOB · 2020Article
- Hydrogen peroxide penetration into the pulp chamber during conventional in-office bleaching and diode laser-assisted bleaching with three different wavelengths.Laser therapy · 2019Article
- Effectiveness of Low-Level Laser Therapy during Tooth Movement: A Randomized Clinical Trial.Materials (Basel, Switzerland) · 2019Article
- In vitro comparison of an Er:YAG laser-activated bleaching system with different light-activated bleaching systems for color change, surface roughness, and enamel bond strength.Lasers in medical science · 2018Article
- [Evaluation of the change in luminosity and sensitivity in laser-assisted teeth whitening: a randomized controlled clinical trial].Revista cientifica odontologica (Universidad Cientifica del Sur)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis systematic review (PROSPERO register: CRD42016053140) investigated the influence of different types of light on the pulp tissue during dental bleaching. MATERIALS AND
methodsTwo independent authors conducted a systematic search and risk of bias evaluations. An electronic search was undertaken (PubMed/Medline, Embase, The Cochrane Library, and other databases) until May 2017. The population, intervention, comparison, outcomes (PICO) question was: "Does the light in dental bleaching change the response of the pulp to the bleaching procedure?" The intervention involved pulp tissue/cells after bleaching with light, while the comparison involved pulp tissue/cells after bleaching without light. The primary outcome was the inflammation/cytotoxicity observed in pulp after bleaching.
resultsOut of 2210 articles found, 12 articles were included in the review; four were in vivo studies (one study in dogs/others in human), and eight were in vitro studies (cell culture/with artificial pulp chamber or not). The light source used was halogen, light-emitting diode (LED), and laser. Only one in vivo study that used heat to simulate light effects showed significant pulp inflammation. Only two in vitro studies demonstrated that light influenced cell metabolism; one using halogen light indicated negative effects, and the other using laser therapy indicated positive effects. Given that animal and in vitro studies have been identified, there remain some limitations for extrapolation to the human situation. Furthermore, different light parameters were used.
conclusionsThe effects of dental bleaching on the pulp are not influenced by different types of light, but different light parameters can influence these properties. CLINICAL RELEVANCE: There is insufficient evidence about the influence of different types of light on inflammation/cytotoxicity of the pulp.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.