Evidence map›Paper›PMID 29230524›Full record

ArticleEuropean radiology2018

One-view digital breast tomosynthesis as a stand-alone modality for breast cancer detection: do we need more?

Alejandro Rodriguez-Ruiz, Albert Gubern-Merida, Mechli Imhof-Tas, Susanne Lardenoije, Alexander J T Wanders, Ingvar Andersson, Sophia Zackrisson, Kristina Lång, Magnus Dustler, Nico Karssemeijer and 2 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Alejandro Rodriguez-RuizDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein 10, Post 766, 6525 GA, Nijmegen, The Netherlands.
Albert Gubern-MeridaDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein 10, Post 766, 6525 GA, Nijmegen, The Netherlands.
Mechli Imhof-TasDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein 10, Post 766, 6525 GA, Nijmegen, The Netherlands.
Susanne LardenoijeDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein 10, Post 766, 6525 GA, Nijmegen, The Netherlands.
Alexander J T WandersBevolkingsonderzoek Zuid-West Borstkanker, Laan 20, 2512 GB, Den Haag, The Netherlands.
Ingvar AnderssonUnilabs Breast Center, Skåne University Hospital, Jan Waldenströms gata 22, SE-20502, Malmö, Sweden.
Sophia ZackrissonDiagnostic Radiology, Department of Translational Medicine, Lund University, Skåne University Hospital, SE-20502, Malmö, Sweden.
Kristina LångUnilabs Breast Center, Skåne University Hospital, Jan Waldenströms gata 22, SE-20502, Malmö, Sweden.
Magnus DustlerDiagnostic Radiology, Department of Translational Medicine, Lund University, Skåne University Hospital, SE-20502, Malmö, Sweden.
Nico KarssemeijerDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein 10, Post 766, 6525 GA, Nijmegen, The Netherlands.
Ritse M MannDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein 10, Post 766, 6525 GA, Nijmegen, The Netherlands.
Ioannis SechopoulosDepartment of Radiology and Nuclear Medicine, Radboud University Medical Centre, Geert Grooteplein 10, Post 766, 6525 GA, Nijmegen, The Netherlands. Ioannis.sechopoulos@radboudumc.nl.ORCID http://orcid.org/0000-0001-9615-8205
Radboud University Nijmegen · NLLund University · SEBorstkanker Onderzoek Groep · NLSkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection. MATERIALS AND

methodsSix radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT). The second session involved only 2v-DM. Lesions were scored using BI-RADS® and level of suspiciousness (1-10). Sensitivity, specificity, receiver operating characteristic (ROC) and jack-knife alternative free-response ROC (JAFROC) were computed.

resultsOn average, 1v-DBT was non-inferior to any of the other protocols in terms of JAFROC figure-of-merit, area under ROC curve, sensitivity or specificity (p>0.391). While readers inexperienced with 1v-DBT screening improved their sensitivity when adding more images (69-79 %, p=0.019), experienced readers showed similar sensitivity (76 %) and specificity (70 %) between 1v-DBT and 2v-DM+2v-DBT (p=0.482). Subanalysis by lesion type and breast density showed no difference among modalities.

conclusionDetection performance with 1v-DBT is not statistically inferior to 2v-DM or to 2v-DM+2v-DBT; its use as a stand-alone modality might be sufficient for readers experienced with this protocol. KEY POINTS: • One-view breast tomosynthesis is not inferior to two-view digital mammography. • One-view DBT is not inferior to 2-view DM plus 2-view DBT. • Training may lead to 1v-DBT being sufficient for screening.

Indexed as

AdultAgedAged, 80 and overBreastBreast NeoplasmsFemaleHumansMammographyMiddle AgedRetrospective StudiesROC CurveBreast cancerDigital breast tomosynthesisDigital mammographyJack-knife alternative free-response receiver operating characteristicReceiver operating characteristic

Identifiers

PMID29230524
PMCPMC5882639
OpenAlexW2772378140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.