ReviewGastroenterology report2017
From genetics and epigenetics to the future of precision treatment for obesity.
Review in Gastroenterology report, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- Adipokine profiles and genetic variants of leptin receptor, adiponectin, and ghrelin pathways in obesity: prospective 12-month outcomes after bariatric interventions.Frontiers in endocrinology · 2026Observational
- Food and Health Literacy in Patients Awaiting Metabolic-Bariatric Surgery.Obesity facts · 2025Article
- The Increase in Childhood Obesity and Its Association with Hypertension during Pandemics.Journal of clinical medicine · 2023Review
- Use of Edible, Medicinal, and Aromatic Plants in Various Health Disorders: A Cross-Sectional Evaluation among Inhabitants in the Area of Thrace, North-Eastern Greece.International journal of environmental research and public health · 2022Article
- Review
- Review
- Metabolic regulation of kisspeptin - the link between energy balance and reproduction.Nature reviews. Endocrinology · 2020Review
- Presence of CC Genotype for rs17773430 Could Affect the Percentage of Excess Weight Loss 1 Year After Bariatric Surgery: Tehran Obesity Treatment Study (TOTS).Obesity surgery · 2020Article
- Childhood and Adolescent Obesity: A Review.Frontiers in pediatrics · 2020Review
- Promises of Nanotherapeutics in Obesity.Trends in endocrinology and metabolism: TEM · 2019Review
- Clinical epigenetics: seizing opportunities for translation.Nature reviews. Genetics · 2019Review
- Ileal transposition rapidly improves glucose tolerance and gradually improves insulin resistance in non-obese type 2 diabetic rats.Gastroenterology report · 2018Article
- The role of visceral adipose tissue on improvement in insulin sensitivity following Roux-en-Y gastric bypass: a study in Chinese diabetic patients with mild and central obesity.Gastroenterology report · 2018Article
- MiR-499/PRDM16 axis modulates the adipogenic differentiation of mouse skeletal muscle satellite cells.Human cell · 2018Article
- Influence of Being Embodied in an Obese Virtual Body on Shopping Behavior and Products Perception in VR.Frontiers in robotics and AI · 2018Article
- Physiologic and pharmacologic considerations in morbid obesity and bariatric anesthesia.Saudi journal of anaesthesiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity has become a major global health problem, epitomized by excess accumulation of body fat resulting from an imbalance between energy intake and expenditure. The treatments for obesity range from modified nutrition and additional physical activity, to drugs or surgery. But the curative effect of each method seems to vary between individuals. With progress in the genetics and epigenetics of obesity, personalization of the clinical management of obesity may be at our doorstep. This review presents an overview of our current understanding of the genetics and epigenetics of obesity and how these findings influence responses to treatments. As bariatric surgery is the most effective long-term treatment for morbid obesity, we pay special attention to the association between genetic factors and clinical outcomes of bariatric surgery. Finally, we discuss the prospects for precision obesity treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.