Evidence map›Paper›PMID 29230188›Full record

ReviewFrontiers in neurology2017

Control of Rest:Activity by a Dopaminergic Ultradian Oscillator and the Circadian Clock.

Clément Bourguignon, Kai-Florian Storch

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Correlation between Rhythmic Changes in Body Temperature of Small Passerine Birds (Chloris chloris) and Nontidal Gravity Fluctuation in a 12- to 30-min Period Range.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2025
    Article
  5. Ultradian Rest-activity Rhythms Induced by Quinpirole in Mice Using Wavelet Analysis.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Article
  6. Article
  7. A Method for Predicting Ultradian Body Temperature Rhythms in Small Animals.Bulletin of experimental biology and medicine · 2024
    Article
  8. Multiple ultradian rhythms of metabolism, body temperature and activity in Djungarian hamsters.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Article
  9. Article
  10. Article
  11. Changes of Locomotor Activity by Dopamine D2, D3 Agonist Quinpirole in Mice Using Home-cage Monitoring System.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023
    Article
  12. Article
  13. Article
  14. Fluctuations in the Rate of Radioactive Decay of the Natural Potassium-40 Isotope Can Potentially Affect the Periodic "Spontaneous" Activity of Animals.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2023
    Article
  15. Review
  16. Article
  17. Coupling-dependent metabolic ultradian rhythms in confluent cells.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Clément BourguignonIntegrated Program in Neuroscience, McGill University, Montreal, QC, Canada.
Kai-Florian StorchDouglas Mental Health University Institute, Montreal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is long-standing evidence for rhythms in locomotor activity, as well as various other aspects of physiology, with periods substantially shorter than 24 h in organisms ranging from fruit flies to humans. These ultradian oscillations, whose periods frequently fall between 2 and 6 h, are normally well integrated with circadian rhythms; however, they often lack the period stability and expression robustness of the latter. An adaptive advantage of ultradian rhythms has been clearly demonstrated for the common vole, suggesting that they may have evolved to confer social synchrony. The cellular substrate and mechanism of ultradian rhythm generation have remained elusive so far, however recent findings-the subject of this review-now indicate that ultradian locomotor rhythms rely on an oscillator based on dopamine, dubbed the dopaminergic ultradian oscillator (DUO). These findings also reveal that the DUO period can be lengthened from <4 to >48 h by methamphetamine treatment, suggesting that the previously described methamphetamine-sensitive (circadian) oscillator represents a long-period manifestation of the DUO.

Indexed as

biological rhythmscircadian clockdopaminergic ultradian oscillatordopamine transporterrest:activity

Identifiers

PMID29230188
PMCPMC5711773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.