ArticleNature neuroscience2018
Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry.
Article in Nature neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 75 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 4 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- The Effects of Food Advertisements on Food Intake and Neural Activity: A Systematic Review and Meta-Analysis of Recent Experimental Studies.Advances in nutrition (Bethesda, Md.) · 2023Pooled it
- Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci.Translational psychiatry · 2021Pooled it
- A systematic review and meta-analysis of delay discounting and cannabis use.Experimental and clinical psychopharmacology · 2021Pooled it
- Delay discounting of different outcomes: Review and theory.Journal of the experimental analysis of behavior · 2020Pooled it
- Neurobehavioral correlates of obesity are largely heritable.Proceedings of the National Academy of Sciences of the United States of America · 2018Trial
- Associations between polygenic risk for obesity, body mass index and cognitive performance: Age as moderating factor.Brain, behavior, & immunity - health · 2026Article
- The Genoeconomics of Impulsive Intertemporal Choice: A Critical Review.Journal of the experimental analysis of behavior · 2026Review
- eQTL analysis: A bridge from genome to mechanism.Genes & diseases · 2026Review
- Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health.Molecular psychiatry · 2026Article
- Machine learning-based computational validation of the Addictions Neuroclinical Assessment framework in relation to hazardous drinking.Journal of psychiatry & neuroscience : JPN · 2026Article
- Impulsivity and pain attentional bias in veterans receiving care for chronic non-malignant pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- The nosology of addiction as a medical condition: a concise history and review of contemporary perspectives.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Genetic and Phenotypic Associations of the Polygenic Score of Delay Discounting and Life History Traits.American journal of human biology : the official journal of the Human Biology Council · 2026Article
- Externalizing as a common genetic influence for a broad spectrum of substance use and behavioral conditions: A developmental perspective from the Avon Longitudinal Study of Parents and Children.Addiction (Abingdon, England) · 2025Article
- Genome-Wide Association Studies of Delay Discounting and Impulsive Personality Traits in Children From the Adolescent Behavior and Cognitive Development Study.Genes, brain, and behavior · 2025Article
- Genomic structural equation modeling of impulsivity and risk-taking traits reveals three latent factors distinctly associated with brain structure and development.bioRxiv : the preprint server for biology · 2025Article
- Delay discounting data in the Adolescent Brain Cognitive Development (ABCD) study: Modeling and analysis considerations.Experimental and clinical psychopharmacology · 2025Article
- Genetic Propensity for Delay Discounting and Educational Attainment in Adults Are Associated With Delay Discounting in Preadolescents: Findings From the Adolescent Brain Cognitive Development Study.Genes, brain, and behavior · 2025Article
- Longitudinal characterization of impulsivity phenotypes boosts signal for genomic correlates and heritability.Molecular psychiatry · 2025Article
- Framing as a mechanism to overcome the temptation of bad habits.Frontiers in behavioral neuroscience · 2025Review
15 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
13 authors at 8 institutions in 3 countries.
Funding
Abstract
Delay discounting (DD), the tendency to discount the value of delayed versus current rewards, is elevated in a constellation of diseases and behavioral conditions. We performed a genome-wide association study of DD using 23,127 research participants of European ancestry. The most significantly associated single-nucleotide polymorphism was rs6528024 (P = 2.40 × 10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.