Evidence map›Paper›PMID 29230052›Full record

ArticleNature neuroscience2018

Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo.

Anna M Krasnow, Marc C Ford, Leonardo E Valdivia, Stephen W Wilson, David Attwell

Abstract read
In one paragraph

Article in Nature neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 187 citations in OpenAlex.

  1. Article
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  8. A computational roadmap to activity-dependent myelination.Frontiers in computational neuroscience · 2026
    Article
  9. Review
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  11. Article
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  14. TMEM63A, associated with hypomyelinating leukodystrophies, is an evolutionarily conserved regulator of myelination.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Anna M KrasnowDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, UK. anna.krasnow.12@ucl.ac.uk.ORCID 0000-0003-3240-511X
Marc C FordDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, UK.ORCID 0000-0003-0472-2652
Leonardo E ValdiviaDepartment of Cell and Developmental Biology, University College London, London, UK.
Stephen W WilsonDepartment of Cell and Developmental Biology, University College London, London, UK.ORCID 0000-0002-8557-5940
David AttwellDepartment of Neuroscience, Physiology & Pharmacology, University College London, London, UK. d.attwell@ucl.ac.uk.ORCID 0000-0003-3618-0843
University College London · GBUniversidad Mayor · CL

Funding

Medical Research Council MR/L003775/1Wellcome Trust
6 · The paper itself

Abstract

How action potentials regulate myelination by oligodendrocytes is uncertain. We show that neuronal activity raises [Ca

Indexed as

Action PotentialsAnimalsAnimals, Genetically ModifiedAxonsCalciumChelating AgentsClustered Regularly Interspaced Short Palindromic RepeatsEgtazic AcidLuminescent ProteinsMivacuriumMyelin Basic ProteinMyelin SheathNeuromuscular Nondepolarizing AgentsNeuronsOligodendrogliaSodium Channel Blockers1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acidCalciumChelating AgentsEgtazic AcidLuminescent ProteinsMivacuriumMyelin Basic ProteinNeuromuscular Nondepolarizing AgentsSodium Channel Blockerssox10 protein, zebrafishSOXE Transcription FactorsTetrodotoxinZebrafish Proteins

Identifiers

PMID29230052
PMCPMC6478117
OpenAlexW2771532739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.